Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 1/20 | 0.64 |
| ▸ | CA6 | P23280 | 1/20 | 0.64 |
| ▸ | CA5A | P35218 | 1/20 | 0.64 |
| ▸ | CA7 | P43166 | 1/20 | 0.64 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.64 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.64 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.64 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | MGLL | Q99685 | 2/20 | 0.48 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.44 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.44 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.44 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.44 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.44 |
| ▸ | P4HB | P07237 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylboronic Acid SCHEMBL4453 | 0.80 | — | — | |
| Phenylboronic Acid SCHEMBL8628436 | 0.80 | ENPP2 (1.00) | CA4CA6CA5ACA7ENPP2 | |
| Phenylboronic Acid SCHEMBL6701482 | 0.78 | ENPP2 (0.74) | CA4CA6CA5ACA7ENPP2 | |
| Phenylboronic Acid SCHEMBL28944102 | 0.78 | ENPP2 (0.74) | CA4CA6CA5ACA7ENPP2 | |
| Phenylboronic Acid SCHEMBL23824843 | 0.78 | ENPP2 (0.74) | CA4CA6CA5ACA7ENPP2 | |
| Phenylboronic Acid SCHEMBL17202516 | 0.78 | ENPP2 (0.82) | CA4CA6CA5ACA7ENPP2 | |
| Phenylboronic Acid SCHEMBL4446883 | 0.77 | ENPP2 (0.93) | CA4CA6CA5ACA7ENPP2 | |
| Phenylboronic Acid SCHEMBL22683683 | 0.77 | ENPP2 (0.93) | CA4CA6CA5ACA7ENPP2 | |
| Phenylboronic Acid SCHEMBL21820815 | 0.77 | ENPP2 (0.93) | CA4CA6CA5ACA7ENPP2 | |
| Phenylboronic Acid SCHEMBL3176519 | 0.77 | ENPP2 (0.93) | CA4CA6CA5ACA7ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1891019-A2 | 2,6-SUBSTITUTED-4-MONOSUBSTITUTEDAMINO-PYRIMIDINE AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | Aventis Pharmaceuticals Inc. (US) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006044732-A2 | 2, 6-SUBSTITUTED-4-MONOSUBSTITUTEDAMINO-PYRIMIDINE AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS | AVENTIS PHARMACEUTICALS INC. (US) | 2006-04-27 | — | — | WO | disclosed |