Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | GALR2 | O43603 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | CCR6 | P51684 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3180920 | 0.90 | HPGD (0.47) | ALDH1A1SMN1; SMN2MAPTKMT2AATM | |
| SCHEMBL7422107 | 0.90 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2GAAMAPTKMT2A | |
| SCHEMBL7502224 | 0.86 | HPGD (0.43) | ALDH1A1SMN1; SMN2MAPTKMT2AATM | |
| SCHEMBL17936438 | 0.83 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2GAAMAPTKMT2A | |
| SCHEMBL9587746 | 0.82 | NPC1 (0.40) | ALDH1A1SMN1; SMN2GAAMAPTKMT2A | |
| SCHEMBL9587365 | 0.81 | ALDH1A1 (0.38) | ALDH1A1SMN1; SMN2GAAMAPTKMT2A | |
| SCHEMBL9587361 | 0.81 | ALDH1A1 (0.40) | ALDH1A1SMN1; SMN2GAAMAPTKMT2A | |
| SCHEMBL9587742 | 0.81 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2GAAMAPTKMT2A | |
| SCHEMBL30443207 | 0.80 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2GAAMAPTKMT2A | |
| SCHEMBL3976878 | 0.80 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2GAAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1891053-A1 | METHOD FOR OBTAINING BENZIMIDAZOLE DERIVATIVES AND INTERMEDIATES THEREOF | Quimica Sintetica, S.A. (ES) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006134078-A1 | METHOD FOR OBTAINING BENZIMIDAZOLE DERIVATIVES AND INTERMEDIATES THEREOF | QUIMICA SINTETICA, S.A. (ES) | 2006-12-21 | — | — | WO | disclosed |