Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3133913 | 0.84 | ESR1 (0.34) | ESR1ALDH1A1 | |
| SCHEMBL6533645 | 0.84 | HTR2A (0.39) | ESR1ALDH1A1 | |
| SCHEMBL3068540 | 0.78 | ESR1 (0.49) | ESR1ALDH1A1 | |
| SCHEMBL4620312 | 0.77 | ESR1 (0.38) | ESR1ALDH1A1 | |
| SCHEMBL3074106 | 0.76 | BCL2L1 (0.49) | ESR1ALDH1A1 | |
| SCHEMBL3069374 | 0.71 | LPL (0.39) | ALDH1A1 | |
| SCHEMBL5601135 | 0.71 | ESR1 (0.48) | ESR1 | |
| SCHEMBL3135618 | 0.70 | ESR1 (0.54) | ESR1ALDH1A1 | |
| SCHEMBL3075044 | 0.70 | ESR1 (0.50) | ESR1 | |
| SCHEMBL3082749 | 0.69 | NR1I2 (0.43) | ESR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1891026-A2 | CYCLOALKYLIDENE COMPOUNDS AS SELECTIVE ESTROGEN RECEPTOR MODULATORS | Smithkline Beecham Corporation (US) | 2008-02-27 | — | — | EP | claimed |
| WO-2006127871-A2 | CYCLOALKYLIDENE COMPOUNDS AS SELECTIVE ESTROGEN RECEPTOR MODULATORS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-11-30 | — | — | WO | claimed |