Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.64 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.58 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.58 |
| ▸ | TNKS | O95271 | 1/20 | 0.58 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.58 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.58 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.53 |
| ▸ | FEN1 | P39748 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | KMO | O15229 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865063 | 0.84 | PARP10 (0.67) | PARP10PARP14TNKSPARP15TNKS2 | |
| SCHEMBL30434552 | 0.82 | PARP10 (0.83) | AKR1C3PARP10PARP14TNKSPARP15 | |
| SCHEMBL2531295 | 0.82 | PARP10 (0.83) | AKR1C3PARP10PARP14TNKSPARP15 | |
| SCHEMBL1383788 | 0.81 | PARP1 (0.69) | NPC1MEN1KMT2AMAOB | |
| Hydrochloric Acid SCHEMBL28772951 | 0.81 | PARP10 (0.80) | AKR1C3PARP10PARP14TNKSPARP15 | |
| SCHEMBL28534850 | 0.81 | AKR1C3 (0.60) | AKR1C3PARP10PARP14TNKSPARP15 | |
| SCHEMBL9615921 | 0.80 | FURIN (0.48) | PARP10PARP14TNKSPARP15TNKS2 | |
| Methyl Alcohol SCHEMBL8784315 | 0.79 | PARP10 (0.77) | AKR1C3PARP10PARP14TNKSPARP15 | |
| Dimethylamine SCHEMBL9864604 | 0.79 | PARP10 (0.59) | PARP10PARP14TNKSPARP15TNKS2 | |
| SCHEMBL21887184 | 0.78 | AKR1C3 (0.78) | AKR1C3PARP10PARP14TNKSPARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409565-A1 | Rubber composition useful for tires | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-01-23 | — | — | EP | claimed |
| EP-1896417-A1 | LINEAR UREA MIMICS ANTAGONISTS OF P2Y1 RECEPTOR USEFUL IN THE TREATMENT OF THROMBOTIC CONDITIONS | Brystol-Myers Squibb Company (US) | 2008-03-12 | — | — | EP | disclosed |
| WO-2007002584-A1 | LINEAR UREA MIMICS ANTAGONISTS OF P2Y1 RECEPTOR USEFUL IN THE TREATMENT OF THROMBOTIC CONDITIONS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-01-04 | — | — | WO | disclosed |
| EP-0409565-A1 | Rubber composition useful for tires | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-01-23 | — | — | EP | disclosed |