Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.49 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.47 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.47 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.47 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | TNKS | O95271 | 1/20 | 0.45 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.45 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.45 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9865063 | 0.93 | PARP10 (0.67) | PARP10SMN1; SMN2SRD5A2ERCC5FEN1 | |
| Dimethylamine SCHEMBL27722244 | 0.84 | MAPT (0.48) | SMN1; SMN2HPGDTSHRHTTALDH1A1 | |
| SCHEMBL9864943 | 0.81 | MMP13 (0.54) | PARP10SMN1; SMN2HPGDTSHRHTT | |
| SCHEMBL8897038 | 0.80 | PARP10 (0.53) | PARP10SMN1; SMN2SRD5A2ERCC5FEN1 | |
| SCHEMBL1162822 | 0.79 | PARP10 (0.60) | PARP10SMN1; SMN2SRD5A2ERCC5FEN1 | |
| SCHEMBL4619224 | 0.79 | AKR1C3 (0.64) | PARP10ERCC5FEN1PARP15PARP14 | |
| SCHEMBL9864000 | 0.78 | PARP10 (0.52) | PARP10HPGDPARP15PARP14ALDH1A1 | |
| SCHEMBL524788 | 0.76 | MAPT (0.56) | SMN1; SMN2HPGDTSHRHTTALDH1A1 | |
| Diphenylether SCHEMBL28021330 | 0.76 | LTA4H (0.67) | PARP10SMN1; SMN2SRD5A2TSHRKMT2A | |
| SCHEMBL10764118 | 0.76 | PARP10 (0.56) | PARP10SMN1; SMN2SRD5A2ERCC5FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0409565-A1 | Rubber composition useful for tires | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-01-23 | — | — | EP | disclosed |