SCHEMBL4619430

SCHEMBL4619430

[O]CCN1C(=O)C=CC1=O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 11/20 0.65
FAAH O00519 5/20 0.65
ALDH1A1 P00352 2/20 0.62
LMNA P02545 2/20 0.62
MAPT P10636 2/20 0.62
NPSR1 Q6W5P4 2/20 0.62
HSP90AA1 P07900 1/20 0.62
TLR9 Q9NR96 1/20 0.62
TP53 P04637 1/20 0.62
PKM P14618 1/20 0.62
HPGD P15428 1/20 0.62
XBP1 P17861 1/20 0.62
MAPK1 P28482 1/20 0.62
HTT P42858 1/20 0.62
RECQL P46063 1/20 0.62
RAB9A P51151 1/20 0.62
SMN1; SMN2 Q16637 1/20 0.62
GPR35 Q9HC97 1/20 0.62
GPR55 Q9Y2T6 1/20 0.62
PTGS1 P23219 7/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14678413 0.84 MGLL (0.77) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL145737 0.84 MGLL (0.77) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL3726898 0.83 MGLL (0.75) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL5061849 0.79 MGLL (0.81) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL331378 0.79 MGLL (0.88) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL155748 0.79 MGLL (1.00) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL17629426 0.78 MGLL (0.59) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL20351983 0.77 MGLL (1.00) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL258626 0.77 MGLL (1.00) MGLLFAAHALDH1A1LMNAMAPT
SCHEMBL818349 0.77 MGLL (1.00) MGLLFAAHALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2004861-A2 COOPERATIVE PROBES AND METHODS OF USING THEM Arcxis Biotechnologies, Inc. (US) 2008-12-24 EP disclosed
EP-1893741-A1 CELL-BASED MICROARRAYS, AND METHODS FOR THEIR PREPARATION AND USE Beckman Coulter, Inc. (US) 2008-03-05 EP disclosed
WO-2007114986-A2 COOPERATIVE PROBES AND METHODS OF USING THEM ARCXIS BIOTECHNOLOGIES, INC. (US) 2007-10-11 WO disclosed
WO-2007001817-A1 CELL-BASED MICROARRAYS, AND METHODS FOR THEIR PREPARATION AND USE BECKMAN COULTER, INC. (US) 2007-01-04 WO disclosed