⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4952091 | 0.73 | — | — | |
| SCHEMBL910558 | 0.71 | — | — | |
| SCHEMBL10382613 | 0.69 | — | — | |
| SCHEMBL910592 | 0.61 | — | — | |
| SCHEMBL6315960 | 0.60 | — | — | |
| SCHEMBL7159584 | 0.59 | — | — | |
| SCHEMBL17873075 | 0.57 | — | — | |
| SCHEMBL18622046 | 0.55 | — | — | |
| SCHEMBL283093 | 0.55 | — | — | |
| SCHEMBL161626 | 0.55 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103450218-B | As the indoles three also ring derivatives of CRTH2 receptor antagonist | SHANDONG HENRY MEDICAL SCIENCE AND TECHNOLOGY CO., LTD. (CN) | 2015-12-23 | — | — | CN | disclosed |
| CN-104418820-A | Carboxylic acid derivative as lysophosphatidic acid receptor antagonist | KBP BIOSCIENCES CO LTD | 2015-03-18 | — | — | CN | disclosed |
| CN-103450218-A | Indole tricyclic derivative as CRTH2 receptor antagonist | SHANDONG HENGLI MEDICAL TECHNOLOGY CO LTD | 2013-12-18 | — | — | CN | disclosed |
| CN-103373996-A | Bicyclic derivatives serving as CRTH2 receptor antagonist | Shandong henry medical science and technology co ltd | 2013-10-30 | — | — | CN | disclosed |
| CN-101184747-B | Cyano anthranilamide insecticides | SYNGENTA PARTICIPATIONS AG | 2012-08-08 | — | — | CN | disclosed |
| US-20120065320-A1 | FLUORINE-CONTAINING 1,6-DIENE ETHER COMPOUND AND FLUORINE-CONTAINING POLYMER | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-03-15 | — | — | US | disclosed |
| US-7977374-B2 | Thiophene and thiazole substituted trifluoroethanone derivatives as histone deacetylase (HDAC) inhibitors | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2011-07-12 | — | — | US | disclosed |
| CN-101061110-B | Heterlcyclic diamide insecticides | SYNGENTA PARTICIPATIONS AG | 2010-09-29 | — | — | CN | disclosed |
| US-7799825-B2 | Thiophene and thiazole substituted trifluoroethanone derivatives as histone deacetylase (HDAC) inhibitors | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI SPA (IT) | 2010-09-21 | — | — | US | disclosed |
| EP-1871760-B1 | CYANO ANTHRANILAMIDE INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2010-08-11 | — | — | EP | disclosed |
| US-7601743-B2 | Cyano anthranilamide insecticides | SYNGENTA CROP PROTECTION, INC. (US) | 2009-10-13 | — | — | US | disclosed |
| US-20090156591-A1 | Thiophene and Thiazole Substituted trifluoroethanone Derivatives as Histone Deacetylase (Hdac) Inhibitors | MSD ITALIA S.R.L. (IT) | 2009-06-18 | — | — | US | disclosed |
| US-20090076101-A1 | Thiophene and Thiazole Substituted Trifluoroethanone Derivatives as Histone Deacetylase (HDAC) Inhibitors | MSD ITALIA S.R.L. (IT) | 2009-03-19 | — | — | US | disclosed |
| US-20080182750-A1 | Cyano Anthranilamide Insecticides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-07-31 | — | — | US | disclosed |
| CN-101184747-A | Cyano anthranilamide insecticides | SYNGENTA PARTICIPATIONS AG (CH) | 2008-05-21 | — | — | CN | disclosed |
| EP-1900730-A1 | Process for the preparation of anthranilamide derivatives | Syngeta Participations AG (CH) | 2008-03-19 | — | — | EP | disclosed |
| CN-101061110-A | Novel insecticides | SYNGENTA PARTICIPATIONS AG (CH) | 2007-10-24 | — | — | CN | disclosed |