Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 17/20 | 0.64 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | FAP | Q12884 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL149732 | 1.00 | DPP4 (0.64) | DPP4DPP8DPP7DRD2DRD3 | |
| SCHEMBL149731 | 1.00 | DPP4 (0.64) | DPP4DPP8DPP7DRD2DRD3 | |
| SCHEMBL149730 | 1.00 | DPP4 (0.64) | DPP4DPP8DPP7DRD2DRD3 | |
| SCHEMBL12064538 | 0.91 | DPP4 (0.58) | DPP4DPP8DPP7DRD2DRD3 | |
| SCHEMBL14722977 | 0.91 | DPP4 (0.58) | DPP4DPP8DPP7DRD2DRD3 | |
| SCHEMBL14722978 | 0.91 | DPP4 (0.58) | DPP4DPP8DPP7DRD2DRD3 | |
| SCHEMBL1725958 | 0.86 | DPP4 (0.63) | DPP4DRD2DRD3CCR5 | |
| SCHEMBL147330 | 0.86 | DPP4 (0.63) | DPP4DRD2DRD3CCR5 | |
| SCHEMBL147328 | 0.86 | DPP4 (0.63) | DPP4DRD2DRD3CCR5 | |
| SCHEMBL147329 | 0.86 | DPP4 (0.63) | DPP4DRD2DRD3CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |