Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.45 |
| ▸ | HRH2 | P25021 | 5/20 | 0.43 |
| ▸ | HRH1 | P35367 | 5/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.42 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.41 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4621353 | 0.96 | MEN1 (0.45) | MEN1HRH3HRH2HRH1CACNA1B | |
| Oxalic Acid SCHEMBL4483558 | 0.93 | MEN1 (0.44) | MEN1HRH3HRH2HRH1CACNA1B | |
| Oxalic Acid SCHEMBL4490074 | 0.89 | CCR3 (0.43) | MEN1HRH3HRH2HRH1CACNA1B | |
| SCHEMBL6094850 | 0.86 | HRH3 (0.50) | MEN1HRH3HRH2HRH1CACNA1B | |
| SCHEMBL6095491 | 0.85 | HRH3 (0.60) | MEN1HRH3HRH2HRH1CACNA1B | |
| Oxalic Acid SCHEMBL4486076 | 0.85 | PAX8 (0.41) | MEN1HRH3CCR3 | |
| SCHEMBL7243006 | 0.85 | HRH3 (0.44) | MEN1HRH3HRH2HRH1CACNA1B | |
| SCHEMBL5965540 | 0.84 | MEN1 (0.48) | MEN1HRH3HRH2HRH1CACNA1B | |
| SCHEMBL2967483 | 0.82 | KCNH2 (0.48) | MEN1HRH3HRH2HRH1CACNA1B | |
| SCHEMBL6095697 | 0.82 | CCR3 (0.43) | MEN1HRH3HRH2HRH1CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720544-B1 | NOVEL AZABICYCLIC DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2008-03-19 | — | — | EP | disclosed |