SCHEMBL4619726

SCHEMBL4619726

CCCCC/C=C\C/C=C\C/C=C\CCCCC(=O)O[C@@H](CO)C(OP(=O)([O-])OCC[N+](C)(C)C)C(=O)CCCCCCCCC

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.64
SMN1; SMN2 Q16637 1/20 0.51
NR5A2 O00482 1/20 0.51
NR5A1 Q13285 1/20 0.51
S1PR1 P21453 2/20 0.50
RECQL P46063 1/20 0.50
MAPT P10636 2/20 0.47
FAAH O00519 1/20 0.46
HPGD P15428 1/20 0.46
CNR1 P21554 1/20 0.46
CNR2 P34972 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
LMNA P02545 1/20 0.45
ESR1 P03372 1/20 0.45
ADORA3 P0DMS8 1/20 0.45
CDC25A P30304 1/20 0.45
AGTR1 P30556 1/20 0.45
AKT1 P31749 1/20 0.45
ADRA1A P35348 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4619498 1.00 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2NR5A2NR5A1S1PR1
SCHEMBL479610 1.00 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2NR5A2NR5A1S1PR1
SCHEMBL479563 1.00 ALDH1A1 (0.64) ALDH1A1SMN1; SMN2NR5A2NR5A1S1PR1
SCHEMBL1576782 0.99 ALDH1A1 (0.66) ALDH1A1SMN1; SMN2NR5A2NR5A1S1PR1
SCHEMBL2561609 0.99 ALDH1A1 (0.66) ALDH1A1SMN1; SMN2NR5A2NR5A1S1PR1
SCHEMBL37559 0.97 ALDH1A1 (0.60) ALDH1A1SMN1; SMN2NR5A2NR5A1S1PR1
SCHEMBL671456 0.97 ALDH1A1 (0.60) ALDH1A1SMN1; SMN2NR5A2NR5A1S1PR1
SCHEMBL479222 0.97 ALDH1A1 (0.60) ALDH1A1SMN1; SMN2NR5A2NR5A1S1PR1
SCHEMBL672371 0.97 ALDH1A1 (0.60) ALDH1A1SMN1; SMN2NR5A2NR5A1S1PR1
SCHEMBL479198 0.97 ALDH1A1 (0.60) ALDH1A1SMN1; SMN2NR5A2NR5A1S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1885377-A2 STRUCTURED PHOSPHOLIPIDS FOR TREATING AUTOIMMUNE AND NEURODEGENERATIVE DISEASES BTG INTERNATIONAL LIMITED (GB) 2008-02-13 EP disclosed
WO-2006056783-A2 STRUCTURED PHOSPHOLIPIDS FOR TREATING AUTOIMMUNE AND NEURODEGENERATIVE DISEASES BTG INTERNATIONAL LIMITED (GB) 2006-06-01 WO disclosed