Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA4 | P22748 | 3/20 | 0.41 |
| ▸ | CA6 | P23280 | 3/20 | 0.41 |
| ▸ | CA5A | P35218 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.41 |
| ▸ | F13A1 | P00488 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | THPO | P40225 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CASP2 | P42575 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3298655 | 0.97 | HDAC6 (0.51) | HDAC6ALOX15CA12CA2CA4 | |
| SCHEMBL6254320 | 0.95 | HDAC6 (0.56) | HDAC6ALOX15CA12CA2CA4 | |
| Trifluoroacetic Acid SCHEMBL1274124 | 0.94 | HDAC6 (0.47) | HDAC6ALOX15CA12CA2CA4 | |
| Trifluoroacetic Acid SCHEMBL1273482 | 0.94 | HDAC6 (0.47) | HDAC6ALOX15CA12CA2CA4 | |
| SCHEMBL1484427 | 0.92 | HDAC6 (0.56) | HDAC6ALOX15CA12CA2CA4 | |
| SCHEMBL1274080 | 0.89 | HDAC6 (0.51) | HDAC6ALOX15CA12CA2CA4 | |
| Spermine SCHEMBL3134527 | 0.85 | HDAC6 (0.67) | HDAC6ALOX15CA12CA2CA4 | |
| Spermine SCHEMBL674873 | 0.85 | HDAC6 (0.67) | HDAC6ALOX15CA12CA2CA4 | |
| SCHEMBL8777348 | 0.80 | HDAC6 (0.43) | HDAC6ALOX15CA12CA2CA4 | |
| Trifluoroacetic Acid SCHEMBL7533514 | 0.79 | CA14 (0.53) | HDAC6ALOX15CA12CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893232-A2 | NEW ADJUVANT | GLAXO GROUP LIMITED (GB) | 2008-03-05 | — | — | EP | disclosed |
| WO-2006136460-A2 | NEW ADJUVANT | GLAXO GROUP LIMITED (GB) | 2006-12-28 | — | — | WO | disclosed |