Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | CA5A | P35218 | 4/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.43 |
| ▸ | CA12 | O43570 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA4 | P22748 | 3/20 | 0.43 |
| ▸ | CA6 | P23280 | 3/20 | 0.43 |
| ▸ | CA7 | P43166 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.43 |
| ▸ | CA3 | P07451 | 3/20 | 0.43 |
| ▸ | F13A1 | P00488 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | THPO | P40225 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1484427 | 0.97 | HDAC6 (0.56) | HDAC6CA5ACA5BCA12CA2 | |
| Trifluoroacetic Acid SCHEMBL1274124 | 0.95 | HDAC6 (0.47) | HDAC6CA5ACA5BCA12CA2 | |
| Trifluoroacetic Acid SCHEMBL1273482 | 0.95 | HDAC6 (0.47) | HDAC6CA5ACA5BCA12CA2 | |
| SCHEMBL6254320 | 0.93 | HDAC6 (0.56) | HDAC6CA5ACA5BCA12CA2 | |
| Trifluoroacetic Acid SCHEMBL3298655 | 0.92 | HDAC6 (0.51) | HDAC6CA5ACA5BCA12CA2 | |
| Trifluoroacetic Acid SCHEMBL4619732 | 0.89 | HDAC6 (0.51) | HDAC6CA5ACA5BCA12CA2 | |
| SCHEMBL8777348 | 0.84 | HDAC6 (0.43) | HDAC6CA5ACA5BCA12CA2 | |
| SCHEMBL8415301 | 0.82 | HDAC6 (0.42) | HDAC6CA5ACA5BCA12CA2 | |
| SCHEMBL2128045 | 0.77 | PAOX (0.52) | CA5ACA5BCA12CA2CA4 | |
| Trifluoroacetic Acid SCHEMBL5548189 | 0.75 | HDAC6 (0.54) | HDAC6CA5ACA5BCA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110045027-A1 | Adjuvant | GLAXO GROUP LIMITED (GB) | 2011-02-24 | — | — | US | disclosed |
| EP-1569694-B1 | POLYAMINE CONJUGATES WITH ACIDIC RETINOIDS AND PREPARATION THEREOF | PAPAIOANNOU DIONYSIOS (GR) | 2009-11-25 | — | — | EP | disclosed |
| US-7517913-B2 | Polyamine conjugates with acidic retinoids and preparation thereof | PAPAIOANNOU DIONYSIOS | 2009-04-14 | — | — | US | disclosed |
| US-20060189696-A1 | Polyamine conjugates with acidic retinoids and preparation thereof | PAPAIOANNOU DIONYSIOS | 2006-08-24 | — | — | US | disclosed |
| EP-1569694-A1 | POLYAMINE CONJUGATES WITH ACIDIC RETINOIDS AND PREPARATION THEREOF | Papaioannou, Dionysios (GR) | 2005-09-07 | — | — | EP | disclosed |
| WO-2004018001-A1 | POLYAMINE CONJUGATES WITH ACIDIC RETINOIDS AND PREPARATION THEREOF | PAPAIOANNOU DIONYSIOS (GR) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110045027-A1 | Adjuvant | TLR3, TLR9, TLR7 | HDAC6 2662/4885CA5A 3309/4885CA5B 3253/4885 |
| US-20060189696-A1 | Polyamine conjugates with acidic retinoids and preparation thereof | RNASEL, RNASEH1, SNRPE | HDAC6 674/4885CA5A 3307/4885CA5B 2853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.