SCHEMBL4619735

SCHEMBL4619735

Oc1ccc(CCCC(Br)Br)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.54
ESR2 Q92731 2/20 0.54
ADRA2A P08913 3/20 0.50
SLC6A2 P23975 3/20 0.50
ADORA3 P0DMS8 2/20 0.50
TACR2 P21452 2/20 0.50
SLC6A4 P31645 2/20 0.50
SLC6A3 Q01959 2/20 0.50
KDM4E B2RXH2 2/20 0.50
ALDH1A1 P00352 2/20 0.50
LMNA P02545 1/20 0.50
SHBG P04278 1/20 0.50
TP53 P04637 1/20 0.50
CYP3A4 P08684 1/20 0.50
HSPD1 P10809 1/20 0.50
ADRB3 P13945 1/20 0.50
HTR2C P28335 1/20 0.50
HSPE1 P61604 1/20 0.50
HIF1A Q16665 1/20 0.50
TST Q16762 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2875692 0.89 FDFT1 (0.37) ESR1ADRA2ASLC6A2ADORA3TACR2
SCHEMBL4618538 0.86 ESR1 (0.59) ESR1ESR2ADRA2ASLC6A2ADORA3
SCHEMBL21698806 0.82 ESR1 (0.59) ESR1ESR2ADRA2ASLC6A2ADORA3
SCHEMBL2876020 0.81 MAOB (0.39) ESR1ADRA2ASLC6A2ADORA3TACR2
SCHEMBL2078829 0.80 ESR1 (0.53) ESR1ESR2ADRA2ASLC6A2ADORA3
SCHEMBL9861541 0.80 ESR1 (0.56) ESR1ESR2ADRA2ASLC6A2ADORA3
SCHEMBL104946 0.78 ESR1 (0.55) ESR1ESR2ADRA2ASLC6A2ADORA3
SCHEMBL1171041 0.78 ESR1 (0.77) ESR1ESR2ADRA2ASLC6A2ADORA3
SCHEMBL245139 0.78 ESR1 (0.77) ESR1ESR2ADRA2ASLC6A2ADORA3
SCHEMBL449737 0.78 ESR1 (0.77) ESR1ESR2ADRA2ASLC6A2ADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115087702-A Styrene resin composition, flame-retardant styrene resin composition, molded article, and patch antenna PS日本株式会社 2022-09-20 CN disclosed
US-20180327671-A1 FLAME RETARDANT LIQUID SOLUTION, POLYURETHANE FOAM-FORMING COMPOSITIONS, POLYURETHANE FOAM AND ARTICLES MADE THEREFROM ICL-IP AMERICA INC. 2018-11-15 US disclosed
EP-1893680-A1 FLAME RETARDANT COMPOSITION EXHIBITING SUPERIOR THERMAL STABILITY AND FLAME RETARDING PROPERTIES AND USE THEREOF ALBEMARLE CORPORATION (US) 2008-03-05 EP disclosed
US-20070018143-A1 Flame retardant composition exhibiting superior thermal stability and flame retarding properties and use thereof ALBEMARLE CORPORATION 2007-01-25 US disclosed
WO-2006132900-A1 FLAME RETARDANT COMPOSITION EXHIBITING SUPERIOR THERMAL STABILITY AND FLAME RETARDING PROPERTIES AND USE THEREOF ALBEMARLE CORPORATION (US) 2006-12-14 WO disclosed
EP-1627013-A2 STABILIZED FLAME RETARDANT ADDITIVES AND THEIR USE ALBEMARLE CORPORATION (US) 2006-02-22 EP disclosed
EP-1127917-B1 Flame-retardant thermoplastic resin composition AJINOMOTO KK (JP) 2005-11-30 EP disclosed
WO-2004104098-A2 STABILIZED FLAME RETARDANT ADDITIVES AND THEIR USE ALBEMARLE CORPORATION (US) 2004-12-02 WO disclosed
US-20040229982-A1 Stabilized flame retardant additives and their use GOOSSENS DANIELLE F (BE) 2004-11-18 US disclosed
US-6500889-B2 BROMINATED FLAME RETARDANT, DOLOMITE AND ONE OF: HYDROTALCITE, ZINC-SUBSTITUTED HYDROTALCITE, OR ZEOLITE; HEAT STABILIZING AJINOMOTO CO., INC. (JP) 2002-12-31 US disclosed
US-20010044488-A1 Flame-retarded thermoplastic resin composition AJINOMOTO CO. INC. (JP) 2001-11-22 US disclosed
EP-1127917-A1 Flame-retardant thermoplastic resin composition Ajinomoto Co., Inc. (JP) 2001-08-29 EP disclosed