SCHEMBL4618538

SCHEMBL4618538

Oc1ccc(CCC(Br)Br)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.59
ESR2 Q92731 2/20 0.59
CA2 P00918 1/20 0.52
ALDH1A1 P00352 3/20 0.50
ADRA2A P08913 3/20 0.50
SLC6A2 P23975 3/20 0.50
KDM4E B2RXH2 3/20 0.50
HTR1A P08908 1/20 0.50
CYP2C19 P33261 1/20 0.50
HTR3A P46098 1/20 0.50
BACE1 P56817 1/20 0.50
TAAR1 Q96RJ0 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
KMT2A Q03164 2/20 0.48
BLM P54132 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
LTA4H P09960 1/20 0.48
TMEM97 Q5BJF2 1/20 0.45
SIGMAR1 Q99720 1/20 0.45
OPRK1 P41145 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2875373 0.87 GFER (0.36) ESR1ESR2CA2TAAR1TDP1
SCHEMBL4619735 0.86 ESR1 (0.54) ESR1ESR2CA2ALDH1A1ADRA2A
SCHEMBL11816431 0.82 ESR1 (0.54) ESR1ESR2CA2ALDH1A1ADRA2A
SCHEMBL7270279 0.78 ESR1 (0.62) ESR1ESR2CA2ALDH1A1ADRA2A
SCHEMBL104626 0.76 ESR1 (0.59) ESR1ESR2CA2ALDH1A1ADRA2A
SCHEMBL69344 0.76 ESR1 (1.00) ESR1ESR2CA2ALDH1A1ADRA2A
SCHEMBL3873458 0.76 ESR1 (1.00) ESR1ESR2CA2ALDH1A1ADRA2A
SCHEMBL4616731 0.75 TAAR1 (0.54) ESR1ESR2CA2ALDH1A1SLC6A2
SCHEMBL4192867 0.75 TDP1 (0.52) ALDH1A1TAAR1TDP1HSD17B10
(+)-Hannokinol SCHEMBL23229864 0.74 ESR1 (0.56) ESR1ESR2CA2ALDH1A1ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115087702-A Styrene resin composition, flame-retardant styrene resin composition, molded article, and patch antenna PS日本株式会社 2022-09-20 CN disclosed
US-20180327671-A1 FLAME RETARDANT LIQUID SOLUTION, POLYURETHANE FOAM-FORMING COMPOSITIONS, POLYURETHANE FOAM AND ARTICLES MADE THEREFROM ICL-IP AMERICA INC. 2018-11-15 US disclosed
CN-101193961-A Flame retardant composition exhibiting excellent thermal stability and flame retardancy and use thereof ALBEMARLE CORP (US) 2008-06-04 CN disclosed
EP-1893680-A1 FLAME RETARDANT COMPOSITION EXHIBITING SUPERIOR THERMAL STABILITY AND FLAME RETARDING PROPERTIES AND USE THEREOF ALBEMARLE CORPORATION (US) 2008-03-05 EP disclosed
US-20070018143-A1 Flame retardant composition exhibiting superior thermal stability and flame retarding properties and use thereof ALBEMARLE CORPORATION 2007-01-25 US disclosed
WO-2006132900-A1 FLAME RETARDANT COMPOSITION EXHIBITING SUPERIOR THERMAL STABILITY AND FLAME RETARDING PROPERTIES AND USE THEREOF ALBEMARLE CORPORATION (US) 2006-12-14 WO disclosed
CN-1788044-A Stabilized flame retardant additives and their use ALBEMARLE CORP (US) 2006-06-14 CN disclosed
EP-1627013-A2 STABILIZED FLAME RETARDANT ADDITIVES AND THEIR USE ALBEMARLE CORPORATION (US) 2006-02-22 EP disclosed
EP-1127917-B1 Flame-retardant thermoplastic resin composition AJINOMOTO KK (JP) 2005-11-30 EP disclosed
CN-1228377-C Fireretardant thermoplastic resin composition AJINOMOTO KK (JP) 2005-11-23 CN disclosed
EP-1409586-A4 POLYESTER / POLYCARBONATE BLEND COMPOSITION ENGINEERED PLASTICS CORP (US) 2005-03-16 EP disclosed
WO-2004104098-A2 STABILIZED FLAME RETARDANT ADDITIVES AND THEIR USE ALBEMARLE CORPORATION (US) 2004-12-02 WO disclosed
US-20040229982-A1 Stabilized flame retardant additives and their use GOOSSENS DANIELLE F (BE) 2004-11-18 US disclosed
EP-1409586-A2 POLYESTER / POLYCARBONATE BLEND COMPOSITION Engineered Plastics Corporation (US) 2004-04-21 EP disclosed
WO-2003004561-A2 POLYESTER / POLYCARBONATE BLEND COMPOSITION ENGINEERED PLASTICS CORPORATION (US) 2003-01-16 WO disclosed
US-6500889-B2 BROMINATED FLAME RETARDANT, DOLOMITE AND ONE OF: HYDROTALCITE, ZINC-SUBSTITUTED HYDROTALCITE, OR ZEOLITE; HEAT STABILIZING AJINOMOTO CO., INC. (JP) 2002-12-31 US disclosed
US-20010044488-A1 Flame-retarded thermoplastic resin composition AJINOMOTO CO. INC. (JP) 2001-11-22 US disclosed
US-6296979-B1 ACOUSTICS FUJI XEROX CO., LTD. (JP) 2001-10-02 US disclosed
CN-1312325-A Fireretardant thermoplastic resin composition AJINOMOTO KK (JP) 2001-09-12 CN disclosed
EP-1127917-A1 Flame-retardant thermoplastic resin composition Ajinomoto Co., Inc. (JP) 2001-08-29 EP disclosed