Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 2/20 | 0.46 |
| ▸ | ACE | P12821 | 2/20 | 0.46 |
| ▸ | CPA1 | P15085 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6677809 | 0.90 | CTNNB1 (0.63) | CTNNB1TDP1HRH4SLC1A3SLC1A2 | |
| SCHEMBL7287691 | 0.85 | CTNNB1 (0.58) | CTNNB1TDP1HRH4SLC1A3SLC1A2 | |
| SCHEMBL7267021 | 0.85 | CTNNB1 (0.58) | CTNNB1TDP1HRH4SLC1A3SLC1A2 | |
| SCHEMBL7268294 | 0.85 | CTNNB1 (0.58) | CTNNB1TDP1HRH4SLC1A3SLC1A2 | |
| SCHEMBL10477725 | 0.84 | CTNNB1 (0.54) | CTNNB1TDP1HRH4SLC1A3SLC1A2 | |
| SCHEMBL7352579 | 0.84 | CYP1A2 (0.65) | CTNNB1TDP1HRH4SLC1A3SLC1A2 | |
| SCHEMBL9194477 | 0.84 | CPA1 (0.57) | CTNNB1TDP1HRH4SLC1A3SLC1A2 | |
| SCHEMBL6444456 | 0.84 | CTNNB1 (0.56) | CTNNB1TDP1HRH4SLC1A3SLC1A2 | |
| SCHEMBL3814684 | 0.84 | CTNNB1 (0.56) | CTNNB1TDP1HRH4SLC1A3SLC1A2 | |
| SCHEMBL7429100 | 0.84 | CPA1 (0.57) | CTNNB1TDP1HRH4SLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1883620-A1 | ß-AMINO ACID DERIVATIVES | Pfizer Limited (GB) | 2008-02-06 | — | — | EP | claimed |
| WO-2006120544-A1 | β-AMINO ACID DERIVATIVES | PFIZER LIMITED (GB) | 2006-11-16 | — | — | WO | claimed |
| WO-2005030735-A1 | TRIAZINES DERIVATIVES AS CELL ADHESION INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2005-04-07 | — | — | WO | claimed |
| EP-1883620-A1 | ß-AMINO ACID DERIVATIVES | Pfizer Limited (GB) | 2008-02-06 | — | — | EP | disclosed |
| WO-2006120544-A1 | β-AMINO ACID DERIVATIVES | PFIZER LIMITED (GB) | 2006-11-16 | — | — | WO | disclosed |
| EP-1572213-A1 | METHOD OF TREATMENT OF TRANSPLANT REJECTION | Pfizer Products Inc. (US) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004047843-A1 | METHOD OF TREATMENT OF TRANSPLANT REJECTION | PFIZER PRODUCTS INC. (US) | 2004-06-10 | — | — | WO | disclosed |