Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 4/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 11/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.41 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.39 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.39 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.39 |
| ▸ | PTGIR | P43119 | 2/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4620672 | 0.74 | PPARD (0.44) | PPARDPPARGPPARAPTGDR2PTGDR | |
| SCHEMBL4178415 | 0.74 | PPARD (0.68) | PPARDPPARGPPARAPTGDR2 | |
| SCHEMBL4196468 | 0.67 | PPARD (0.51) | PPARDPPARGPPARAPTGDR2PTGDR | |
| SCHEMBL4182987 | 0.67 | PPARD (0.57) | PPARDPPARAPTGDR2PTGDR | |
| SCHEMBL10730557 | 0.65 | PTGDR2 (0.68) | PTGDR2PTGDR | |
| SCHEMBL4185340 | 0.64 | PPARD (0.70) | PPARDPPARGPPARAPTGDR2 | |
| SCHEMBL5510509 | 0.64 | PPARD (0.52) | PPARDPPARGPPARAPTGDR2 | |
| SCHEMBL3273104 | 0.63 | PTGDR2 (0.59) | PTGDR2PTGDRSLC6A9 | |
| SCHEMBL25433566 | 0.62 | L3MBTL1 (0.59) | KCNJ6KCNJ5KCNJ3FFAR4 | |
| SCHEMBL18780289 | 0.62 | KDM4E (0.49) | PPARDPPARGPPARAPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1945620-A2 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | IRM LLC (BM) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007056366-A2 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | IRM LLC (BM) | 2007-05-18 | — | — | WO | disclosed |