Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 20/20 | 0.61 |
| ▸ | KLKB1 | P03952 | 14/20 | 0.61 |
| ▸ | F10 | P00742 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL462070 | 1.00 | F11 (0.61) | F11KLKB1F10 | |
| SCHEMBL390271 | 0.93 | F11 (0.71) | F11KLKB1F10 | |
| SCHEMBL390272 | 0.93 | F11 (0.71) | F11KLKB1F10 | |
| SCHEMBL392607 | 0.91 | F11 (0.69) | F11KLKB1 | |
| SCHEMBL392608 | 0.91 | F11 (0.69) | F11KLKB1 | |
| SCHEMBL391789 | 0.91 | F11 (0.69) | F11KLKB1F10 | |
| SCHEMBL391790 | 0.91 | F11 (0.69) | F11KLKB1F10 | |
| SCHEMBL393065 | 0.90 | F11 (0.73) | F11KLKB1F10 | |
| SCHEMBL392354 | 0.88 | F11 (0.56) | F11KLKB1F10 | |
| SCHEMBL391752 | 0.85 | F11 (0.68) | F11KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101778-B2 | Five-membered heterocycles useful as serine protease inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-01-24 | — | — | US | claimed |