Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 9/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | CASP1 | P29466 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31092876 | 0.93 | TLR7 (0.38) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL142891 | 0.93 | TLR7 (0.38) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL30448090 | 0.92 | TLR7 (0.39) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL143565 | 0.92 | TLR7 (0.39) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL12245200 | 0.83 | APP (0.42) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL3274002 | 0.83 | TLR7 (0.50) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL146701 | 0.82 | TLR7 (0.44) | TLR7POLBTLR8 | |
| SCHEMBL14866402 | 0.82 | TLR7 (0.37) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL12245236 | 0.80 | TLR7 (0.36) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL29988385 | 0.80 | TLR7 (0.39) | TLR7PDE4DPIM1TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1945253-A2 | ADMINSTRATION ROUTES FOR PRIMING/BOOSTING WITH INFLUENZA VACCINES | Novartis Vaccines and Diagnostics S.r.l. (IT) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007052057-A2 | ADMINSTRATION ROUTES FOR PRIMING/BOOSTING WITH INFLUENZA VACCINES | NOVARTIS VACCINES AND DIAGNOSTICS SRL (IT) | 2007-05-10 | — | — | WO | disclosed |