SCHEMBL4620869

SCHEMBL4620869

CC(C)C/C(C(=O)O)=C(/CC(C)C)C(=O)O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
CA2 P00918 1/20 0.46
GRIK1 P39086 2/20 0.41
MMP1 P03956 1/20 0.39
MMP2 P08253 1/20 0.39
MMP3 P08254 1/20 0.39
MMP9 P14780 1/20 0.39
MMP13 P45452 1/20 0.39
GRIA4 P48058 1/20 0.38
GRIK3 Q13003 1/20 0.38
GRIK5 Q16478 1/20 0.38
CYP2C19 P33261 2/20 0.38
CYP2D6 P10635 1/20 0.38
LMNA P02545 1/20 0.36
HPGD P15428 1/20 0.36
RNPEP Q9H4A4 1/20 0.36
SLC7A5 Q01650 1/20 0.36
CACNA2D1 P54289 2/20 0.36
CACNB3 P54284 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL610561 1.00 ALDH1A1 (0.50) ALDH1A1TDP1CA2GRIK1MMP1
SCHEMBL610562 1.00 ALDH1A1 (0.50) ALDH1A1TDP1CA2GRIK1MMP1
SCHEMBL8778791 0.97 ALDH1A1 (0.48) ALDH1A1TDP1CA2GRIK1MMP1
SCHEMBL5611081 0.89 GRIK1 (0.42) ALDH1A1TDP1CA2GRIK1MMP1
SCHEMBL5611085 0.89 GRIK1 (0.42) ALDH1A1TDP1CA2GRIK1MMP1
SCHEMBL28146034 0.86 ALDH1A1 (0.43) ALDH1A1TDP1CA2GRIK1MMP1
SCHEMBL28255243 0.84 ALDH1A1 (0.42) ALDH1A1TDP1CA2GRIK1MMP1
SCHEMBL6510401 0.82 ALDH1A1 (0.46) ALDH1A1TDP1CA2GRIK1MMP1
SCHEMBL17386530 0.82 ALDH1A1 (0.40) ALDH1A1TDP1CA2GRIK1MMP1
SCHEMBL17386531 0.82 ALDH1A1 (0.40) ALDH1A1TDP1CA2GRIK1MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3110867-B1 COATING COMPOSITIONS COMPRISING DIISOCYANATE CHAIN EXTENDED BISASPARTATES COATINGS FOREIGN IP CO LLC (US) 2021-10-06 EP claimed
EP-3156433-B1 COATING COMPOSITIONS INCLUDING A POLYISOCYANATE CHAIN EXTENDED NH FUNCTIONAL PREPOLYMER AXALTA COATING SYSTEMS IP CO (US) 2018-06-27 EP claimed
EP-3110869-B1 COATING COMPOSITIONS COMPRISING DIISOCYANATE CHAIN EXTENDED BISASPARTATES COATINGS FOREIGN IP CO LLC (US) 2018-04-25 EP claimed
EP-1231206-B1 Stabilized organic peroxidicarbonate compositions ATOFINA CHEM INC (US) 2004-03-17 EP claimed
EP-0244835-B1 LANGMUIR-BLODGETT ULTRATHIN MEMBRANE OF POLYFUMURATE NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1992-08-26 EP claimed
US-9353299-B2 2-cyanoacrylate-based adhesive composition TOAGOSEI CO., LTD. (JP) 2016-05-31 US disclosed
US-20150225627-A1 2-CYANOACRYLATE-BASED ADHESIVE COMPOSITION TOAGOSEI CO., LTD. (JP) 2015-08-13 US disclosed
US-9080087-B2 Reduction in modulus of polyurethane sealants and adhesives CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2015-07-14 US disclosed
US-8697188-B2 Polyurethane systems having non-sag and paintability CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2014-04-15 US disclosed
US-20130267637-A1 Reduction In Modulus of Polyurethane Sealants and Adhesives CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2013-10-10 US disclosed
US-20130059082-A1 Polyurethane Systems Having Non-Sag and Paintability CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2013-03-07 US disclosed
EP-1899393-A1 OIL SOLUBLE COMB POLYMERS Evonik RohMax Additives GmbH (DE) 2008-03-19 EP disclosed
WO-2007003238-A1 OIL SOLUBLE COMB POLYMERS EVONIK ROHMAX ADDITIVES GMBH (DE) 2007-01-11 WO disclosed
EP-0987299-B1 Compositions containing radical-generating agents and phlegmatizers, use and process for the preparation of such compositions ATOCHEM ELF DEUTSCHLAND (DE) 2006-07-26 EP disclosed
EP-0987299-A1 Compositions containing radical-generating agents and phlegmatizers, use and process for the preparation of such compositions Elf Atochem Deutschland GmbH (DE) 2000-03-22 EP disclosed
EP-0697029-B1 AQUEOUS POLYMER DISPERSIONS AND THEIR USE IN THE PRODUCTION OF COATINGS WHICH ARE PERMEABLE TO WATER VAPOUR ROTTA GMBH (DE) 1998-08-26 EP disclosed
US-4220744-A Mass polymerization process VIANOVA KUNSTHARZ, A.G. (AT) 1980-09-02 US disclosed
US-4209599-A ADDITION POLYMERS SYNRES INTERNATIONAL B.V. (NL) 1980-06-24 US disclosed
US-3935151-A Blended latex binder for exterior paints with wet primed adhesion BORDEN, INC. (US) 1976-01-27 US disclosed