Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4619067 | 0.83 | CHRM2 (0.58) | CHRM3HTTPOLBCHRM2CHRM1 | |
| SCHEMBL4878826 | 0.82 | CHRM3 (0.57) | CHRM3CHRM2CHRM1 | |
| SCHEMBL4620147 | 0.81 | ALDH1A1 (0.51) | CHRM3HTTPOLBCHRM2CHRM1 | |
| SCHEMBL5106067 | 0.81 | CHRM3 (0.53) | CHRM3HTTPOLBCHRM2CHRM1 | |
| SCHEMBL3222150 | 0.80 | HTT (0.53) | CHRM3HTTPOLBCHRM2CHRM1 | |
| SCHEMBL4878755 | 0.80 | CHRM3 (0.58) | CHRM3CHRM2CHRM1 | |
| SCHEMBL3214986 | 0.80 | HTT (0.53) | CHRM3HTTPOLBCHRM2CHRM1 | |
| SCHEMBL5246422 | 0.79 | HTT (0.69) | CHRM3HTTPOLBCHRM2CHRM1 | |
| SCHEMBL5250142 | 0.79 | HTT (0.69) | CHRM3HTTPOLBCHRM2CHRM1 | |
| SCHEMBL4179648 | 0.79 | CHRM3 (0.53) | CHRM3HTTPOLBCHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888525-A1 | 3,6-DISUBSTITUTED AZABICYCLO [3.1.0]HEXANE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | Ranbaxy Laboratories Limited (IN) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006117754-A1 | 3,6-DISUBSTITUTED AZABICYCLO [3.1.0] HEXANE DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2006-11-09 | — | — | WO | disclosed |