⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL785934 | 0.96 | TTR (0.43) | — | |
| SCHEMBL3313943 | 0.87 | — | — | |
| SCHEMBL7209053 | 0.79 | — | — | |
| SCHEMBL1371575 | 0.73 | SMN1; SMN2 (0.44) | — | |
| SCHEMBL27637444 | 0.69 | — | — | |
| SCHEMBL10599432 | 0.67 | MGLL (0.47) | — | |
| SCHEMBL236146 | 0.67 | MGLL (0.47) | — | |
| SCHEMBL25928 | 0.64 | TTR (0.50) | — | |
| SCHEMBL19878897 | 0.64 | — | — | |
| SCHEMBL11554965 | 0.64 | TTR (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 14849 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12029739-B2 | SHP2 inhibitor and use thereof | KANAPH THERAPEUTICS INC. (KR) | 2024-07-09 | — | — | US | claimed |
| EP-3972589-B1 | NATRIURETIC PEPTIDE RECEPTOR A AGONISTS USEFUL FOR THE TREATMENT OF CARDIOMETABOLIC DISEASES, KIDNEY DISEASE AND DIABETES | MERCK SHARP & DOHME LLC (US) | 2024-07-03 | — | — | EP | claimed |
| WO-2024131265-A1 | COMPOUND FOR TREATING PI3Kγ-MEDIATED DISEASES AND USE THEREOF | 中国科学院合肥物质科学研究院 | 2024-06-27 | — | — | WO | claimed |
| CN-118239953-A | Compounds for the treatment of PI3K gamma mediated diseases and uses thereof | 中国科学院合肥物质科学研究院 | 2024-06-25 | — | — | CN | claimed |
| US-20240189306-A1 | SHP2 INHIBITOR AND USE THEREOF | KANAPH THERAPEUTICS INC. (KR) | 2024-06-13 | — | — | US | claimed |
| EP-4373835-A1 | MACROCYLIC IMMUNOMODULATORS | Bristol-Myers Squibb Company (US) | 2024-05-29 | — | — | EP | claimed |
| CN-115335431-B | Modified poly (phenylene ether) copolymers, compositions and methods | 高新特殊工程塑料全球技术有限公司 | 2024-05-24 | — | — | CN | claimed |
| WO-2024104425-A1 | KRAS INHIBITOR COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | 广东东阳光药业股份有限公司 | 2024-05-23 | — | — | WO | claimed |
| EP-3702354-B1 | COMPOUND HAVING ERK KINASE INHIBITORY ACTIVITY AND USE THEREOF | HAIHE BIOPHARMA CO LTD (CN) | 2024-05-22 | — | — | EP | claimed |
| EP-3468953-B1 | SUBSTITUTED PYRIDINES AS INHIBITORS OF DNMT1 | GLAXOSMITHKLINE IP DEV LTD (GB) | 2024-05-22 | — | — | EP | claimed |
| US-4379924-A | Cephalosporin derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1983-04-12 | — | — | US | claimed |
| EP-0062834-A1 | Thiocarbamic-acid esters, process for their preparation, medicines containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-10-20 | — | — | EP | claimed |
| EP-0042593-A1 | Aryloxy-propanol amines, process for their preparation and medicines containing these compounds | Roche Diagnostics GmbH (DE) | 1981-12-30 | — | — | EP | claimed |
| US-4256830-A | SUBSTITUTED ALKYNES, ANTIFOGGING | AGFA-GEVAERT, A.G. (DE) | 1981-03-17 | — | — | US | claimed |
| US-4183927-A | Substituted phenylthioalkylamines and compositions thereof | THE DOW CHEMICAL COMPANY (US) | 1980-01-15 | — | — | US | claimed |
| US-4155907-A | Method for inhibiting ADP-induced platelet aggregation using phenylthioalkylamines | THE DOW CHEMICAL COMPANY (US) | 1979-05-22 | — | — | US | claimed |
| US-4137315-A | ANTIMICROBIAL, ANTIFUNGAL, ANTISEPTICS | RHONE-POULENC INDUSTRIES (FR) | 1979-01-30 | — | — | US | claimed |
| US-3994891-A | VASODILATORS | ARMOUR PHARMACEUTICAL COMPANY (US) | 1976-11-30 | — | — | US | claimed |
| US-3956297-A | 9H-Dibenzo[b,f]imidazo[1,2-d][1,4]diazepines | THE UPJOHN COMPANY (US) | 1976-05-11 | — | — | US | claimed |
| US-3950522-A | N-ALKENYL OR N-ALKYNYL THIOAMIDES | SMITHKLINE CORPORATION (US) | 1976-04-13 | — | — | US | claimed |