Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 19/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL463247 | 0.89 | TTK (0.47) | TTK | |
| SCHEMBL457970 | 0.83 | TTK (0.44) | TTK | |
| SCHEMBL457467 | 0.81 | TTK (0.40) | TTK | |
| SCHEMBL463285 | 0.80 | PDE4D (0.43) | TTK | |
| SCHEMBL455417 | 0.80 | TTK (0.75) | TTK | |
| SCHEMBL15271384 | 0.80 | TTK (0.69) | TTK | |
| SCHEMBL463164 | 0.78 | TTK (0.50) | TTK | |
| SCHEMBL456371 | 0.77 | TTK (0.46) | TTK | |
| SCHEMBL15554967 | 0.77 | TTK (0.50) | TTK | |
| SCHEMBL12989349 | 0.76 | TTK (0.46) | TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614063-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | Bayer Intellectual Property GmbH (DE) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012032031-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-15 | — | — | WO | disclosed |