Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 9/20 | 0.63 |
| ▸ | OXTR | P30559 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3137315 | 0.90 | HTR6 (0.77) | HTR6OXTRTSHRALDH1A1 | |
| SCHEMBL3152345 | 0.86 | HTR6 (0.68) | HTR6 | |
| SCHEMBL3148210 | 0.85 | HTR6 (0.74) | HTR6ALDH1A1 | |
| SCHEMBL3146923 | 0.84 | HTR6 (0.66) | HTR6ALDH1A1 | |
| SCHEMBL3138605 | 0.84 | HTR6 (0.66) | HTR6SMN1; SMN2 | |
| SCHEMBL3148297 | 0.84 | HTR6 (0.66) | HTR6KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL3142878 | 0.84 | HTR6 (0.68) | HTR6ALDH1A1 | |
| SCHEMBL3152438 | 0.83 | HTR6 (0.73) | HTR6KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL3152654 | 0.83 | HTR6 (0.66) | HTR6ALDH1A1SMN1; SMN2 | |
| SCHEMBL3148124 | 0.82 | HTR6 (0.66) | HTR6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902733-A1 | Combination of a NMDA-receptor ligand and a compound with 5-HT6 receptor affinity | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2008-03-26 | — | — | EP | disclosed |