Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.32 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.32 |
| ▸ | ITGAL | P20701 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4973068 | 0.76 | CA2 (0.47) | CA2PARP1HTTMTNR1ACYP1B1 | |
| SCHEMBL5320559 | 0.76 | CA2 (0.47) | CA2PARP1HTTMTNR1ACYP1B1 | |
| SCHEMBL437597 | 0.74 | CA2 (0.50) | CA2PARP1NISCHALOX5ITGB2 | |
| SCHEMBL3639081 | 0.74 | CA2 (0.45) | CA2PARP1HTTMTNR1ACYP1B1 | |
| SCHEMBL3632741 | 0.74 | CA2 (0.45) | CA2PARP1HTTMTNR1ACYP1B1 | |
| SCHEMBL9423459 | 0.74 | CA2 (0.45) | CA2PARP1HTTMTNR1ACYP1B1 | |
| SCHEMBL4333283 | 0.74 | CA2 (0.45) | CA2PARP1NISCHHTTMTNR1A | |
| SCHEMBL3763119 | 0.74 | CA2 (0.45) | CA2PARP1NISCHHTTMTNR1A | |
| SCHEMBL3394611 | 0.70 | CA2 (0.42) | CA2PARP1HTTMTNR1ACYP1B1 | |
| SCHEMBL3617768 | 0.70 | MAOB (0.44) | CA2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1905762-A1 | PYRAZOLONE DERIVATIVE | Genecare Research Institute Co., Ltd (JP) | 2008-04-02 | — | — | EP | disclosed |
| EP-1900728-A1 | PHARMACEUTICAL COMPOSITION COMPRISING PYRAZOLONE DERIVATIVE | Genecare Research Institute Co., Ltd (JP) | 2008-03-19 | — | — | EP | disclosed |