Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4621529 | 0.92 | GNRHR (0.31) | GNRHR | |
| SCHEMBL4228389 | 0.91 | GNRHR (0.35) | GNRHR | |
| SCHEMBL4236499 | 0.90 | GNRHR (0.37) | GNRHR | |
| SCHEMBL4233369 | 0.89 | GNRHR (0.36) | GNRHR | |
| SCHEMBL4236694 | 0.88 | GNRHR (0.38) | GNRHR | |
| SCHEMBL4620458 | 0.87 | GNRHR (0.37) | GNRHR | |
| SCHEMBL4237186 | 0.86 | GNRHR (0.35) | GNRHR | |
| SCHEMBL4237638 | 0.86 | GNRHR (0.34) | GNRHR | |
| SCHEMBL4621356 | 0.84 | CYP1A2 (0.33) | GNRHR | |
| SCHEMBL4233283 | 0.84 | GNRHR (0.32) | GNRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896465-A1 | HETEROCYCLIC NON-PEPTIDE GNRH ANTAGONISTS | Takeda Cambridge Limited (GB) | 2008-03-12 | — | — | EP | disclosed |
| WO-2007000582-A1 | HETEROCYCLIC NON-PEPTIDE GNRH ANTAGONISTS | TAKEDA CAMBRIDGE LIMITED (GB) | 2007-01-04 | — | — | WO | disclosed |