Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.66 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.48 |
| ▸ | HRH2 | P25021 | 2/20 | 0.48 |
| ▸ | HRH1 | P35367 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL4489113 | 0.97 | HRH3 (0.62) | HRH3GLAL3MBTL1NPC1RAB9A | |
| SCHEMBL4622753 | 0.91 | HRH3 (0.66) | HRH3GLAL3MBTL1NPC1RAB9A | |
| SCHEMBL4495437 | 0.91 | HRH3 (0.69) | HRH3GLAL3MBTL1HRH2HRH1 | |
| Oxalic Acid SCHEMBL4506368 | 0.88 | HRH3 (0.62) | HRH3GLAL3MBTL1NPC1MEN1 | |
| SCHEMBL4486761 | 0.88 | HRH3 (0.65) | HRH3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL4498063 | 0.87 | HRH3 (0.64) | HRH3GLAL3MBTL1POLB | |
| SCHEMBL4486197 | 0.86 | HRH3 (0.72) | HRH3MEN1KMT2AHRH2HRH1 | |
| SCHEMBL14241012 | 0.86 | HRH3 (0.72) | HRH3MEN1KMT2AHRH2HRH1 | |
| SCHEMBL4622251 | 0.86 | HRH3 (0.62) | HRH3MEN1KMT2AHRH2HRH1 | |
| SCHEMBL4494595 | 0.85 | HRH3 (0.67) | HRH3HRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720544-B1 | NOVEL AZABICYCLIC DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2008-03-19 | — | — | EP | disclosed |