Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.66 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HRH2 | P25021 | 2/20 | 0.48 |
| ▸ | HRH1 | P35367 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL4506368 | 0.97 | HRH3 (0.62) | HRH3NPC1GLAL3MBTL1HRH2 | |
| SCHEMBL4622140 | 0.91 | HRH3 (0.66) | HRH3NPC1GLAL3MBTL1HRH2 | |
| SCHEMBL4486761 | 0.90 | HRH3 (0.65) | HRH3NPC1POLBALDH1A1KMT2A | |
| SCHEMBL4495437 | 0.89 | HRH3 (0.69) | HRH3GLAL3MBTL1HRH2HRH1 | |
| Oxalic Acid SCHEMBL4489113 | 0.88 | HRH3 (0.62) | HRH3NPC1GLAL3MBTL1POLB | |
| SCHEMBL4498063 | 0.87 | HRH3 (0.64) | HRH3GLAL3MBTL1POLBMAOB | |
| SCHEMBL4486197 | 0.86 | HRH3 (0.72) | HRH3HRH2HRH1MAOBALDH1A1 | |
| SCHEMBL14241012 | 0.86 | HRH3 (0.72) | HRH3HRH2HRH1MAOBALDH1A1 | |
| SCHEMBL4621967 | 0.86 | HRH3 (0.65) | HRH3HRH2HRH1MAOBALDH1A1 | |
| SCHEMBL4494595 | 0.85 | HRH3 (0.67) | HRH3HRH2HRH1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720544-B1 | NOVEL AZABICYCLIC DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2008-03-19 | — | — | EP | disclosed |
| EP-1720544-A1 | NOVEL AZABICYCLIC DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Les Laboratoires Servier (FR) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005089747-A1 | NOVEL AZABICYCLIC DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2005-09-29 | — | — | WO | disclosed |