Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 19/20 | 0.70 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.62 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.62 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.62 |
| ▸ | DRD4 | P21917 | 1/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.62 |
| ▸ | HRH2 | P25021 | 1/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.62 |
| ▸ | HRH1 | P35367 | 1/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.62 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.62 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL4486834 | 0.97 | HRH3 (0.66) | HRH3CHRM2CHRM1ADRA2CCHRM3 | |
| SCHEMBL4619979 | 0.90 | HRH3 (0.70) | HRH3DRD2 | |
| SCHEMBL4621668 | 0.90 | HRH3 (0.70) | HRH3DRD2 | |
| SCHEMBL4622331 | 0.88 | HRH3 (0.75) | HRH3DRD2 | |
| SCHEMBL4482326 | 0.88 | HRH3 (0.67) | HRH3DRD2 | |
| SCHEMBL29659792 | 0.87 | HRH3 (0.61) | HRH3CHRM2CHRM1ADRA2CCHRM3 | |
| SCHEMBL29659739 | 0.87 | HRH3 (0.61) | HRH3CHRM2CHRM1ADRA2CCHRM3 | |
| SCHEMBL4621549 | 0.87 | HRH3 (0.66) | HRH3DRD2 | |
| SCHEMBL4622137 | 0.87 | HRH3 (0.66) | HRH3HRH2HRH1DRD2 | |
| Oxalic Acid SCHEMBL4508710 | 0.87 | HRH3 (0.66) | HRH3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111377911-B | Morpholine benzamide compound and application thereof | 江苏恩华药业股份有限公司 | 2022-05-24 | — | — | CN | disclosed |
| EP-1720544-B1 | NOVEL AZABICYCLIC DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2008-03-19 | — | — | EP | disclosed |