Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 16/20 | 0.75 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL4495423 | 0.96 | HRH3 (0.70) | HRH3DRD2HPGDALDH1A1MAOB | |
| SCHEMBL4621668 | 0.91 | HRH3 (0.70) | HRH3DRD2HPGDALDH1A1MAOB | |
| SCHEMBL4619979 | 0.91 | HRH3 (0.70) | HRH3DRD2HPGDALDH1A1MAOB | |
| SCHEMBL29659753 | 0.90 | ALDH1A1 (0.69) | HRH3DRD2HPGDALDH1A1MEN1 | |
| SCHEMBL4482326 | 0.89 | HRH3 (0.67) | HRH3DRD2HPGDALDH1A1MEN1 | |
| Oxalic Acid SCHEMBL4508710 | 0.88 | HRH3 (0.66) | HRH3DRD2HPGDALDH1A1MAOB | |
| SCHEMBL4621549 | 0.88 | HRH3 (0.66) | HRH3DRD2HPGDALDH1A1MEN1 | |
| SCHEMBL4622137 | 0.88 | HRH3 (0.66) | HRH3DRD2HPGDALDH1A1MEN1 | |
| SCHEMBL4621593 | 0.88 | HRH3 (0.66) | HRH3DRD2MAOB | |
| Oxalic Acid SCHEMBL4498003 | 0.88 | HRH3 (0.66) | HRH3DRD2HPGDALDH1A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720544-B1 | NOVEL AZABICYCLIC DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2008-03-19 | — | — | EP | disclosed |