Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | MAOA | P21397 | 4/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | S100A4 | P26447 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.38 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL396140 | 0.75 | MAOA (0.50) | CES1MAOABCHEKMT2AMEN1 | |
| SCHEMBL6552234 | 0.75 | CES1 (0.56) | CES1MAOABCHEKMT2AMEN1 | |
| SCHEMBL9321655 | 0.71 | MAOA (0.50) | CES1MAOABCHEKMT2AMEN1 | |
| SCHEMBL14054414 | 0.71 | MAOA (0.50) | CES1MAOABCHEKMT2AMEN1 | |
| SCHEMBL2566227 | 0.71 | CES1 (0.50) | CES1MAOABCHEKMT2AMEN1 | |
| SCHEMBL10590259 | 0.69 | MAOA (0.48) | CES1MAOABCHEKMT2AMEN1 | |
| SCHEMBL13712393 | 0.68 | CES1 (1.00) | CES1MAOABCHEKMT2AMEN1 | |
| SCHEMBL2319027 | 0.68 | MAOA (0.90) | CES1MAOABCHEKMT2AMEN1 | |
| SCHEMBL10594856 | 0.68 | MAOA (0.47) | CES1MAOABCHEKMT2AMEN1 | |
| SCHEMBL14154630 | 0.67 | CES1 (0.45) | CES1MAOABCHEKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1903031-A2 | Synthesis of Pentafluorosulfanylnaphthalene | Air Products and Chemicals, Inc. (US) | 2008-03-26 | — | — | EP | disclosed |