Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.41 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.40 |
| ▸ | NMT2 | O60551 | 1/20 | 0.39 |
| ▸ | NMT1 | P30419 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4419239 | 1.00 | KMT2A (0.44) | KMT2AMEN1FAAHMAPK1KDM4C | |
| SCHEMBL258528 | 0.84 | FAAH (0.65) | KMT2AMEN1FAAHMAPK1PLA2G10 | |
| SCHEMBL258407 | 0.84 | FAAH (0.65) | KMT2AMEN1FAAHMAPK1PLA2G10 | |
| SCHEMBL258681 | 0.84 | FAAH (0.65) | KMT2AMEN1FAAHMAPK1PLA2G10 | |
| SCHEMBL258719 | 0.84 | FAAH (0.65) | KMT2AMEN1FAAHMAPK1PLA2G10 | |
| SCHEMBL258663 | 0.84 | FAAH (0.65) | KMT2AMEN1FAAHMAPK1PLA2G10 | |
| SCHEMBL258782 | 0.84 | FAAH (0.65) | KMT2AMEN1FAAHMAPK1PLA2G10 | |
| SCHEMBL28619599 | 0.83 | FAAH (0.62) | KMT2AMEN1FAAHMAPK1PLA2G10 | |
| SCHEMBL28475200 | 0.83 | FAAH (0.62) | KMT2AMEN1FAAHMAPK1PLA2G10 | |
| SCHEMBL3277342 | 0.80 | KMT2A (0.36) | KMT2AMEN1FAAHMAPK1PLA2G10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1881956-A1 | 3-(2-(DIMETHYLAMINO)METHYL(CYCLOHEX-1-YL))PHENOL MALEATE AND ITS CRYSTALLINE FORMS | Grünenthal GmbH (DE) | 2008-01-30 | — | — | EP | disclosed |
| EP-1844021-A1 | CRYSTALLINE FORMS OF ROSUVASTATIN CALCIUM SALT | Ciba Specialty Chemicals Holding Inc. (CH) | 2007-10-17 | — | — | EP | disclosed |
| WO-2007009792-A1 | 3-(2-(DIMETHYLAMINO)METHYL(CYCLOHEX-1-YL))PHENOL MALEATE AND ITS CRYSTALLINE FORMS | Grünenthal GmbH (DE) | 2007-01-25 | — | — | WO | disclosed |
| WO-2006079611-A1 | CRYSTALLINE FORMS OF ROSUVASTATIN CALCIUM SALT | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2006-08-03 | — | — | WO | disclosed |