Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 12/20 | 0.37 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28062324 | 0.82 | CHRM3 (0.39) | DPP4CHRM3CARM1PRMT6SMN1; SMN2 | |
| SCHEMBL27539772 | 0.80 | CHRM3 (0.49) | DPP4CHRM3SMN1; SMN2BCHE | |
| SCHEMBL27727639 | 0.80 | MAOB (0.39) | DPP4CHRM3CARM1PRMT6BCHE | |
| SCHEMBL27875126 | 0.79 | NAAA (0.37) | DPP4 | |
| SCHEMBL27662826 | 0.79 | TP53 (0.49) | DPP4SMN1; SMN2 | |
| SCHEMBL27698089 | 0.78 | DPP4 (0.43) | DPP4CHRM3CARM1PRMT6BCHE | |
| SCHEMBL23089331 | 0.78 | CHRM3 (0.46) | DPP4CHRM3SMN1; SMN2 | |
| SCHEMBL28862226 | 0.76 | DPP4 (0.38) | DPP4CHRM3SMN1; SMN2BCHE | |
| SCHEMBL28127651 | 0.76 | DPP4 (0.38) | DPP4CHRM3CARM1PRMT6SMN1; SMN2 | |
| SCHEMBL4569265 | 0.75 | HRH3 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904479-A2 | NOVEL 2,4-DIANILINOPYRIMIDINE DERIVATIVES, THE PREPARATION THEREOF, THEIR USE AS MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS AND, IN PARTICULAR, AS IKK INHIBITORS | Sanofi-Aventis (FR) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007006926-A2 | NOVEL 2,4-DIANILINOPYRIMIDINE DERIVATIVES, THE PREPARATION THEREOF, THEIR USE AS MEDICAMENTS, PHARMACEUTICAL COMPOSITIONS AND, IN PARTICULAR, AS IKK INHIBITORS | SANOFI-AVENTIS (FR) | 2007-01-18 | — | — | WO | disclosed |