Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 2/20 | 0.60 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 5/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4620131 | 1.00 | ITGAV (0.60) | ITGAVADAMTS4NPSR1ALDH1A1HPGD | |
| SCHEMBL4618939 | 1.00 | ITGAV (0.60) | ITGAVADAMTS4NPSR1ALDH1A1HPGD | |
| SCHEMBL14676507 | 0.83 | ITGAV (0.55) | ITGAVNPSR1CASP1HTR6KAT6A | |
| SCHEMBL24429623 | 0.82 | NPSR1 (0.59) | ITGAVNPSR1ALDH1A1HTR6KAT6A | |
| SCHEMBL4622116 | 0.81 | ITGAV (0.70) | ITGAVNPSR1CASP1HTR6KAT6A | |
| SCHEMBL4621521 | 0.81 | ITGAV (0.70) | ITGAVNPSR1CASP1HTR6KAT6A | |
| SCHEMBL4621068 | 0.81 | ITGAV (0.70) | ITGAVNPSR1CASP1HTR6KAT6A | |
| SCHEMBL14798294 | 0.80 | SLC1A3 (0.64) | ITGAVADAMTS4ALDH1A1CASP1KAT6A | |
| SCHEMBL27895996 | 0.80 | SLC1A3 (0.64) | ITGAVADAMTS4ALDH1A1CASP1KAT6A | |
| SCHEMBL10765699 | 0.80 | SLC1A3 (0.64) | ITGAVADAMTS4ALDH1A1CASP1KAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1884230-A1 | PARAKERATOSIS INHIBITOR, PORE-SHRINKING AGENT OR AGENT FOR PREVENTING/AMELIORATING ROUGH SKIN AND EXTERNAL COMPOSITION FOR SKIN | Shiseido Company, Limited (JP) | 2008-02-06 | — | — | EP | disclosed |