Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4622547 | 1.00 | DHODH (0.33) | DHODHVDR | |
| SCHEMBL4622550 | 1.00 | DHODH (0.33) | DHODHVDR | |
| SCHEMBL4622542 | 1.00 | DHODH (0.33) | DHODHVDR | |
| SCHEMBL4622563 | 0.94 | DHODH (0.34) | DHODHVDR | |
| SCHEMBL4622561 | 0.94 | DHODH (0.34) | DHODHVDR | |
| SCHEMBL4622568 | 0.94 | DHODH (0.34) | DHODHVDR | |
| SCHEMBL4622571 | 0.94 | DHODH (0.34) | DHODHVDR | |
| SCHEMBL4621534 | 0.86 | DHODH (0.33) | DHODHVDR | |
| SCHEMBL4621532 | 0.86 | DHODH (0.33) | DHODHVDR | |
| SCHEMBL4621538 | 0.86 | DHODH (0.33) | DHODHVDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080182891-A1 | CHROMANE AND CHROMENE DERIVATIVES AND USES THEREOF | WYETH (US) | 2008-07-31 | — | — | US | disclosed |
| US-7365095-B2 | Chromane and chromene derivatives and uses thereof | WYETH (US) | 2008-04-29 | — | — | US | disclosed |
| EP-1874756-A1 | CHROMANE AND CHROMENE DERIVATIVES AND USES THEREOF | Wyeth (US) | 2008-01-09 | — | — | EP | disclosed |
| US-20060258714-A1 | Chromane and chromene derivatives and uses thereof | WYETH (US) | 2006-11-16 | — | — | US | disclosed |
| WO-2006116165-A1 | CHROMANE AND CHROMENE DERIVATIVES AND USES THEREOF | WYETH (US) | 2006-11-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080182891-A1 | CHROMANE AND CHROMENE DERIVATIVES AND USES THEREOF | HTR1A, HTR2C, CHRM1 | DHODH 4819/4885VDR 154/4885 |
| US-20060258714-A1 | Chromane and chromene derivatives and uses thereof | HTR1A, HTR2C, CHRM1 | DHODH 4819/4885VDR 154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.