SCHEMBL4622616

SCHEMBL4622616

CCCCCC/C=C(\C(=O)O)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 1/20 0.53
CES2 O00748 3/20 0.50
CES1 P23141 3/20 0.50
NAAA Q02083 1/20 0.49
TBXAS1 P24557 1/20 0.48
SOAT2 O75908 1/20 0.46
SOAT1 P35610 1/20 0.46
AKR1C1 Q04828 1/20 0.44
FAAH O00519 2/20 0.43
EPHX2 P34913 2/20 0.43
TDP1 Q9NUW8 1/20 0.43
CNR1 P21554 1/20 0.42
CNR2 P34972 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31575757 1.00 EP300 (0.53) EP300CES2CES1NAAATBXAS1
SCHEMBL8971310 1.00 EP300 (0.53) EP300CES2CES1NAAATBXAS1
SCHEMBL5467265 1.00 EP300 (0.53) EP300CES2CES1NAAATBXAS1
SCHEMBL6258126 1.00 EP300 (0.53) EP300CES2CES1NAAATBXAS1
SCHEMBL6666634 1.00 EP300 (0.53) EP300CES2CES1NAAATBXAS1
SCHEMBL597781 0.98 EP300 (0.50) EP300CES2CES1NAAATBXAS1
SCHEMBL597783 0.98 EP300 (0.50) EP300CES2CES1NAAATBXAS1
SCHEMBL8157814 0.93 CES2 (0.47) EP300CES2CES1NAAATBXAS1
SCHEMBL524133 0.93 CES2 (0.47) EP300CES2CES1NAAATBXAS1
SCHEMBL29033074 0.87 CES2 (0.47) EP300CES2CES1NAAATBXAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3197953-B1 IMPACT-RESISTANT MOULDING MATERIAL WITH IMPROVED CHARACTERISTIC PROFILE EVONIK ROEHM GMBH (DE) 2018-05-23 EP disclosed
EP-3197953-A1 IMPACT-RESISTANT MOLDING MATERIAL HAVING AN IMPROVED CHARACTERISTICS PROFILE Evonik Röhm GmbH (DE) 2017-08-02 EP disclosed
EP-2978785-B1 IMPACT-RESISTANT PMMA WITH IMPROVED OPTICAL PROPERTIES EVONIK ROEHM GMBH (DE) 2017-03-08 EP disclosed
WO-2016046043-A1 IMPACT-RESISTANT MOLDING MATERIAL HAVING AN IMPROVED CHARACTERISTICS PROFILE EVONIK RÖHM GMBH (DE) 2016-03-31 WO disclosed
EP-2978785-A1 PMMA PROVIDED WITH IMPACT RESISTANCE AND HAVING IMPROVED OPTICAL PROPERTIES Evonik Röhm GmbH (DE) 2016-02-03 EP disclosed
WO-2014154543-A1 PMMA PROVIDED WITH IMPACT RESISTANCE AND HAVING IMPROVED OPTICAL PROPERTIES EVONIK RÖHM GMBH (DE) 2014-10-02 WO disclosed
EP-1572769-B1 METHOD FOR PRODUCING AQUEOUS DISPERSIONS EVONIK ROEHM GMBH (DE) 2008-03-19 EP disclosed
EP-1572769-A1 METHOD FOR PRODUCING AQUEOUS DISPERSIONS Röhm GmbH & Co. KG (DE) 2005-09-14 EP disclosed
WO-2004056893-A1 METHOD FOR PRODUCING AQUEOUS DISPERSIONS Röhm GmbH & Co. KG (DE) 2004-07-08 WO disclosed
EP-0522351-B1 Impact modifier ROEHM GMBH (DE) 1997-02-19 EP disclosed
EP-0522351-A1 Impact modifier RÖHM GMBH (DE) 1993-01-13 EP disclosed