Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4622626 | 1.00 | APP (0.51) | APPMAOBATMKDM4EALDH1A1 | |
| SCHEMBL6794103 | 0.84 | EGFR (0.53) | APPATMKDM4EALDH1A1TDP1 | |
| SCHEMBL6794099 | 0.84 | EGFR (0.53) | APPATMKDM4EALDH1A1TDP1 | |
| SCHEMBL28989630 | 0.84 | APP (0.50) | APPATMKDM4EALDH1A1HCAR2 | |
| SCHEMBL3940917 | 0.77 | APP (0.60) | APPATMKDM4EALDH1A1HCAR2 | |
| SCHEMBL11834908 | 0.77 | APP (0.60) | APPATMKDM4EALDH1A1HCAR2 | |
| SCHEMBL18843944 | 0.77 | ATM (0.54) | APPATMKDM4EALDH1A1HCAR2 | |
| SCHEMBL19244396 | 0.77 | KDM4E (0.61) | APPATMKDM4EALDH1A1HCAR2 | |
| SCHEMBL8930462 | 0.77 | ATM (0.54) | APPATMKDM4EALDH1A1HCAR2 | |
| SCHEMBL3940920 | 0.77 | APP (0.60) | APPATMKDM4EALDH1A1HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1368287-B1 | PROCESS FOR A HOMOGENEOUSLY CATALYZED C-C COUPLING REACTION | DSM IP ASSETS BV (NL) | 2008-03-26 | — | — | EP | disclosed |