Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 7/20 | 0.53 |
| ▸ | RARG | P13631 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 3/20 | 0.49 |
| ▸ | MMP3 | P08254 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | GBA1 | P04062 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4622907 | 0.93 | KMT2A (0.57) | KMT2AMAPTALDH1A1KDM4EPKM | |
| SCHEMBL1201631 | 0.81 | MAPT (0.66) | KMT2AMAPTALDH1A1KDM4EPKM | |
| SCHEMBL7920967 | 0.78 | KMT2A (0.60) | KMT2AMAPTALDH1A1KDM4EPKM | |
| SCHEMBL7160716 | 0.77 | MAPT (0.63) | KMT2AMAPTALDH1A1KDM4EPKM | |
| SCHEMBL7160719 | 0.77 | MAPT (0.63) | KMT2AMAPTALDH1A1KDM4EPKM | |
| SCHEMBL3117237 | 0.77 | KMT2A (0.59) | KMT2AMAPTALDH1A1KDM4EPKM | |
| SCHEMBL3117214 | 0.77 | KMT2A (0.59) | KMT2AMAPTALDH1A1KDM4EPKM | |
| SCHEMBL5374848 | 0.75 | PPARG (0.61) | KMT2AMAPTALDH1A1KDM4EPKM | |
| SCHEMBL7914462 | 0.75 | PPARG (0.58) | KMT2AMAPTALDH1A1KDM4EPKM | |
| SCHEMBL5381839 | 0.75 | PPARG (0.58) | KMT2AMAPTALDH1A1KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1905761-A1 | An improved process for the preparation of 4-[2-(methyl-2-pyridinylamino) ethoxy] benzaldehyde, an intermediate for the preparation of rosiglitazone | Cadila Pharmaceuticals Limited (IN) | 2008-04-02 | — | — | EP | disclosed |