Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL378903 | 1.00 | MAPT (0.51) | MAPTGAAGFERPOLBAKR1C3 | |
| SCHEMBL5073489 | 0.86 | AKR1C3 (0.69) | MAPTGAAGFERPOLBAKR1C3 | |
| SCHEMBL5073492 | 0.86 | AKR1C3 (0.69) | MAPTGAAGFERPOLBAKR1C3 | |
| SCHEMBL554744 | 0.84 | AKR1C3 (0.69) | GAAAKR1C3ALDH1A1MEN1KMT2A | |
| SCHEMBL476911 | 0.84 | AKR1C3 (0.69) | GAAAKR1C3ALDH1A1MEN1KMT2A | |
| SCHEMBL5072384 | 0.82 | MAPT (0.50) | MAPTGAAGFERPOLBAKR1C3 | |
| SCHEMBL5072381 | 0.82 | MAPT (0.50) | MAPTGAAGFERPOLBAKR1C3 | |
| SCHEMBL5830527 | 0.82 | AKR1C3 (0.52) | MAPTGAAPOLBAKR1C3ALDH1A1 | |
| SCHEMBL5830531 | 0.82 | AKR1C3 (0.52) | MAPTGAAPOLBAKR1C3ALDH1A1 | |
| SCHEMBL11763819 | 0.79 | KDM4E (0.67) | MAPTPOLBALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1321489-B1 | Preparation and use of a nanocomposite of elastomer and exfoliated clay platelets formed in situ within an elastomer host and articles of manufacture, including tires, having at least one component comprised thereof | GOODYEAR TIRE & RUBBER (US) | 2008-04-30 | — | — | EP | claimed |
| CN-109415649-B | Hydraulic fluid composition | 路博润公司 | 2022-11-08 | — | — | CN | disclosed |
| JP-2005200648-A | GRAFT COPOLYMER, IT'S MANUFACTURING METHOD AND COMPOSITION CONTAINING IT | AFTON CHEMICAL CORP | 2005-07-28 | — | — | JP | disclosed |
| US-5171768-A | Continuous processing in four zones; selective addition of conjugated diene to partially polymerized non-carboxylic monomer; butadiene-itaconic acid-butadiene terpolymer | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1992-12-15 | — | — | US | disclosed |
| US-5135996-A | Using coordination catalysts | TEXACO INC. (US) | 1992-08-04 | — | — | US | disclosed |