SCHEMBL554744

SCHEMBL554744

C/C(=C\c1ccccc1)C(N)=O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.69
MCL1 Q07820 1/20 0.53
ALDH1A1 P00352 2/20 0.52
TSHR P16473 1/20 0.52
HTT P42858 1/20 0.52
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
DHODH Q02127 1/20 0.49
TRPM8 Q7Z2W7 1/20 0.49
SLC9A1 P19634 1/20 0.49
SLC9A3 P48764 1/20 0.49
SLC9A2 Q9UBY0 1/20 0.49
RECQL P46063 1/20 0.48
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
FBP1 P09467 2/20 0.47
GLA P06280 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
PKM P14618 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL476911 1.00 AKR1C3 (0.69) AKR1C3MCL1ALDH1A1TSHRHTT
Phenol SCHEMBL29181787 0.92 AKR1C3 (0.60) AKR1C3MCL1ALDH1A1TSHRHTT
SCHEMBL5830527 0.89 AKR1C3 (0.52) AKR1C3MCL1ALDH1A1HTTNPC1
SCHEMBL5830531 0.89 AKR1C3 (0.52) AKR1C3MCL1ALDH1A1HTTNPC1
SCHEMBL378903 0.84 MAPT (0.51) AKR1C3ALDH1A1TSHRHTTNPC1
SCHEMBL4622685 0.84 MAPT (0.51) AKR1C3ALDH1A1TSHRHTTNPC1
SCHEMBL29158024 0.84 TBXAS1 (0.56) AKR1C3MCL1ALDH1A1NPC1RAB9A
SCHEMBL805622 0.82 AKR1C3 (0.75) AKR1C3ALDH1A1TSHRHTTNPC1
SCHEMBL759655 0.82 AKR1C3 (0.75) AKR1C3ALDH1A1TSHRHTTNPC1
SCHEMBL759656 0.82 AKR1C3 (0.75) AKR1C3ALDH1A1TSHRHTTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 339 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260040695-A1 A METHOD TO GENERATE CONDUCTIVE POLYMER NEWSOUTH INNOVATIONS PTY LTD (AU) 2026-02-05 US claimed
EP-4562077-A1 A METHOD TO GENERATE CONDUCTIVE POLYMER NewSouth Innovations Pty Limited (AU) 2025-06-04 EP claimed
US-12135503-B2 Organometallic photoresists for DUV or EUV lithography INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2024-11-05 US claimed
WO-2024020649-A1 A METHOD TO GENERATE CONDUCTIVE POLYMER NEWSOUTH INNOVATIONS PTY LIMITED (AU) 2024-02-01 WO claimed
WO-2022261721-A1 HEALABLE AND REPROCESSABLE COMPOSITIONS DEAKIN UNIVERSITY (AU) 2022-12-22 WO claimed
US-20220317572-A1 ORGANOMETALLIC PHOTORESISTS FOR DUV OR EUV LITHOGRAPHY INTERNATIONAL BUSINESS MACHINES CORPORATION 2022-10-06 US claimed
EP-3735439-A1 STABLE ORGANIC LIGHT EMITTING COATING Yissum Research Development Company of the Hebrew University of Jerusalem Ltd (IL) 2020-11-11 EP claimed
WO-2019135223-A1 STABLE ORGANIC LIGHT EMITTING COATING YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD (IL) 2019-07-11 WO claimed
EP-3298053-A1 ENERGY CURABLE HYPERBRANCHED POLYCARBONATE POLYOL BACKBONE POLYFUNCTIONAL ACRYLATES BASF Corporation (US) 2018-03-28 EP claimed
EP-3191582-A1 CELL CULTURE SUBSTRATE The University Of Nottingham (GB) 2017-07-19 EP claimed
EP-1562542-B1 PERFUME POLYMERIC PARTICLES PROCTER & GAMBLE (US) 2009-10-14 EP claimed
EP-1660507-B1 PROTEASOME INHIBITORS AND METHODS OF USING THE SAME CEPHALON INC (US) 2009-08-05 EP claimed
US-7504446-B2 Aqueous inks containing colored polymers XEROX CORPORATION (US) 2009-03-17 US claimed
CN-1867572-A proteasome inhibitors and methods of use thereof CEPHALON INC (US) 2006-11-22 CN claimed
EP-1660507-A2 PROTEASOME INHIBITORS AND METHODS OF USING THE SAME CEPHALON, INC. (US) 2006-05-31 EP claimed
US-20060074142-A1 Aqueous inks containing colored polymers XEROX CORPORATION 2006-04-06 US claimed
US-20050107307-A1 Proteasome inhibitors and methods of using the same TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2005-05-19 US claimed
WO-2005021558-A2 PROTEASOME INHIBITORS AND METHODS OF USING THE SAME CEPHALON, INC. (US) 2005-03-10 WO claimed
US-5549807-A Thermoplastic composites formed by electropolymerization of N-substituted methacrylamide monomers THE UNIVERSITY OF CONNECTICUT (US) 1996-08-27 US claimed
US-5238542-A Onto electrically conductive filler THE UNIVERSITY OF CONNECTICUT (US) 1993-08-24 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050107307-A1 Proteasome inhibitors and methods of using the same PSMB11, PSMB5, PSMB6 AKR1C3 2698/4885MCL1 60/4885ALDH1A1 3935/4885
US-20260040695-A1 A METHOD TO GENERATE CONDUCTIVE POLYMER PIEZO1, LCP1, MTCL3 AKR1C3 4848/4885MCL1 2852/4885ALDH1A1 4717/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.