Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4621854 | 0.83 | TP53 (0.31) | — | |
| SCHEMBL7598594 | 0.82 | TDP1 (0.33) | ALDH1A1 | |
| SCHEMBL7009420 | 0.80 | PDCD1 (0.35) | PDCD1CD274HDAC4HDAC2HDAC8 | |
| SCHEMBL1507320 | 0.80 | PDCD1 (0.35) | PDCD1CD274HDAC4HDAC2HDAC8 | |
| SCHEMBL5600529 | 0.73 | PDCD1 (0.39) | PDCD1CD274HDAC4HDAC2HDAC8 | |
| SCHEMBL4623136 | 0.72 | PDCD1 (0.40) | PDCD1CD274HTR7HDAC4HDAC2 | |
| SCHEMBL5084808 | 0.72 | PDCD1 (0.40) | PDCD1CD274HTR7HDAC4HDAC2 | |
| SCHEMBL5690207 | 0.71 | PDCD1 (0.39) | PDCD1CD274HTR7HDAC4HDAC2 | |
| SCHEMBL7920406 | 0.70 | HDAC4 (0.40) | HDAC4HDAC2HDAC8ALDH1A1HSD17B10 | |
| SCHEMBL5608711 | 0.70 | PDCD1 (0.37) | PDCD1CD274HDAC4HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219657-B1 | POLYARYLENE AND METHOD FOR PRODUCTION THEREOF | JAPAN SCIENCE & TECH AGENCY (JP) | 2008-03-19 | — | — | EP | disclosed |
| US-20020052446-A1 | Composition based on monofluorometal complexes | BAYER AKTIENGESELLSCHAFT (DE) | 2002-05-02 | — | — | US | disclosed |