Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | HNF4A | P41235 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7009420 | 0.90 | PDCD1 (0.35) | PDCD1CD274ALDH1A1HSD17B10HDAC4 | |
| SCHEMBL4622699 | 0.80 | PDCD1 (0.34) | PDCD1CD274ALDH1A1HSD17B10HDAC4 | |
| SCHEMBL5600529 | 0.79 | PDCD1 (0.39) | PDCD1CD274ALDH1A1HSD17B10HDAC4 | |
| SCHEMBL5611715 | 0.76 | MEN1 (0.34) | ALDH1A1HSD17B10KDM4ELMNAMAPT | |
| SCHEMBL5608711 | 0.76 | PDCD1 (0.37) | PDCD1CD274ALDH1A1HSD17B10HDAC4 | |
| SCHEMBL5084808 | 0.75 | PDCD1 (0.40) | PDCD1CD274ALDH1A1HSD17B10HDAC4 | |
| SCHEMBL4623136 | 0.75 | PDCD1 (0.40) | PDCD1CD274ALDH1A1HSD17B10HDAC4 | |
| SCHEMBL2044120 | 0.73 | ALDH1A1 (0.42) | PDCD1CD274ALDH1A1HSD17B10HDAC4 | |
| SCHEMBL5690207 | 0.73 | PDCD1 (0.39) | PDCD1CD274HDAC4HDAC2HDAC8 | |
| SCHEMBL4453364 | 0.73 | ADORA3 (0.36) | PDCD1CD274ALDH1A1HDAC4HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017188602-A1 | HYBRID SUPPORTED METALLOCENE CATALYST, AND POLYOLEFIN RESIN HAVING EXCELLENT PROCESSABILITY AND USING SAME | 한화케미칼 주식회사 | 2017-11-02 | — | — | WO | disclosed |
| EP-2291419-A2 | POLYMACROMONOMER AND PROCESS FOR PRODUCTION THEREOF | ExxonMobil Chemical Patents Inc. (US) | 2011-03-09 | — | — | EP | disclosed |