Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4621857 | 0.85 | HCRTR1 (0.31) | HCRTR1HCRTR2 | |
| SCHEMBL7053629 | 0.82 | PDCD1 (0.39) | PDCD1CD274HTR7 | |
| SCHEMBL27494089 | 0.81 | PDCD1 (0.34) | PDCD1CD274 | |
| SCHEMBL7009427 | 0.81 | PDCD1 (0.34) | PDCD1CD274HTR7 | |
| SCHEMBL8468224 | 0.80 | PDCD1 (0.33) | PDCD1CD274 | |
| SCHEMBL7039516 | 0.78 | PDCD1 (0.33) | PDCD1CD274 | |
| Hydrochloric Acid SCHEMBL5169310 | 0.78 | PDCD1 (0.33) | PDCD1CD274 | |
| Hydrochloric Acid SCHEMBL20480854 | 0.77 | BRD4 (0.32) | PDCD1CD274 | |
| SCHEMBL7598597 | 0.76 | — | — | |
| SCHEMBL27459241 | 0.76 | PDCD1 (0.31) | PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219657-B1 | POLYARYLENE AND METHOD FOR PRODUCTION THEREOF | JAPAN SCIENCE & TECH AGENCY (JP) | 2008-03-19 | — | — | EP | disclosed |
| US-20020052446-A1 | Composition based on monofluorometal complexes | BAYER AKTIENGESELLSCHAFT (DE) | 2002-05-02 | — | — | US | disclosed |