Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 5/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4623529 | 0.95 | ALDH1A1 (0.35) | TSHRHSD17B10PKMALDH1A1SMN1; SMN2 | |
| SCHEMBL4622374 | 0.89 | ALDH1A1 (0.35) | PKMALDH1A1NLRP3 | |
| SCHEMBL17525712 | 0.89 | ALDH1A1 (0.35) | PKMALDH1A1NLRP3 | |
| SCHEMBL17525717 | 0.85 | ALDH1A1 (0.48) | TSHRPKMALDH1A1POLB | |
| SCHEMBL2443510 | 0.85 | ALDH1A1 (0.48) | TSHRPKMALDH1A1POLB | |
| SCHEMBL3085673 | 0.84 | ALDH1A1 (0.36) | PKMALDH1A1 | |
| SCHEMBL3072474 | 0.81 | ALDH1A1 (0.36) | PKMALDH1A1 | |
| SCHEMBL3081013 | 0.81 | ALDH1A1 (0.36) | PKMALDH1A1 | |
| SCHEMBL3085221 | 0.81 | ALDH1A1 (0.52) | TSHRPKMALDH1A1POLB | |
| SCHEMBL17525724 | 0.77 | HIF1A (0.47) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8940780-B2 | N-acylic aminoacid derivatives, method for the production thereof, pharmacological composition and the use in the form anti-allergic, anti-inflammatory and hypolipidemic agents | OTKRYTOE AKTSIONERNOE OBSCHESTVO OTECHESTVENNYE LEKARSTVA (RU) | 2015-01-27 | — | — | US | claimed |
| EP-1905763-B1 | N-ACYLIC AMINOACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, PHARMACOLOGICAL COMPOSITION AND THE USE IN THE FORM OF ANTI-ALLERGIC, ANTI-INFLAMMATORY AND HYPOLIPIDEMIC AGENTS | NEBOLSIN VLADIMIR EVGENIEVICH (RU) | 2019-05-08 | — | — | EP | disclosed |
| EP-1905763-A1 | N-ACYLIC AMINOACID DERIVATIVES. METHOD FOR THE PRODUCTION THEREOF, PHARMACOLOGICAL COMPOSITION AND THE USE IN THE FORM OF ANTI-ALLERGIC, ANTI-INFLAMMATORY AND HYPOLIPIDEMIC AGENTS | Nebolsin, Vladimir Evgenievich (RU) | 2008-04-02 | — | — | EP | disclosed |