Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.35 |
| ▸ | WDR5 | P61964 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4624575 | 0.89 | TSHR (0.45) | TSHRSLC6A4KCNH2HTR2AHPGD | |
| SCHEMBL1758939 | 0.77 | TSHR (0.54) | TSHRHPGDMEN1ALDH1A1KMT2A | |
| SCHEMBL4623289 | 0.77 | TSHR (0.54) | TSHRCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL3323523 | 0.76 | TSHR (0.49) | TSHRHPGDMEN1ALDH1A1KMT2A | |
| SCHEMBL3323521 | 0.76 | TSHR (0.49) | TSHRHPGDMEN1ALDH1A1KMT2A | |
| SCHEMBL21901873 | 0.75 | TSHR (0.51) | TSHRHPGDMEN1ALDH1A1KMT2A | |
| SCHEMBL4623474 | 0.73 | TSHR (0.56) | TSHRMEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL4623207 | 0.72 | CYP1A2 (0.35) | CYP1A2CYP2D6CYP2C9CYP2C19HPGD | |
| SCHEMBL3326140 | 0.71 | TSHR (0.42) | TSHRHPGDMEN1KMT2AROCK2 | |
| SCHEMBL3326135 | 0.71 | TSHR (0.42) | TSHRHPGDMEN1KMT2AROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1201648-B1 | CARBAMATE DERIVATIVES AND AGRICULTURAL/HORTICULTURAL BACTERICIDES | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2008-04-02 | — | — | EP | disclosed |
| US-6812229-B1 | OXIME SUBSTITUTED PHENYL; RAIN-FAST WITHOUT CROP DAMAGE; CUCUMBER DOWNY MILDEW, APPLE SCAB, WHEAT POWDERY MILDEW, RICE BLAST, CUCUMBER GRAY MOLD, RICE SHEATH BLIGHT, WHEAT BROWN LEAF RUST, WHEAT SEPTORIA LEAF BLOTCH AND CUCUMBER STEM ROT | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2004-11-02 | — | — | US | disclosed |
| EP-1201648-A1 | CARBAMATE DERIVATIVES AND AGRICULTURAL/HORTICULTURAL BACTERICIDES | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2002-05-02 | — | — | EP | disclosed |