Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL28183738 | 0.92 | GAA (0.61) | GAAALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL1275812 | 0.88 | KMT2A (0.72) | GAAALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL28220669 | 0.86 | GAA (0.71) | GAAALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL10393959 | 0.81 | KMT2A (0.64) | GAAALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL29522175 | 0.81 | KDM4E (0.71) | GAAALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL260429 | 0.81 | KDM4E (0.71) | GAAALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL28182823 | 0.80 | GAA (0.52) | GAAALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL31206215 | 0.80 | KMT2A (0.77) | GAAALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL8956204 | 0.80 | KMT2A (0.77) | GAAALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL9724986 | 0.79 | KDM4E (0.67) | GAAALDH1A1KMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108007909-A | Carbon quantum dot is in detection Fe after the modification of 4- naphthyl -3- thiosemicarbazides3+In application | 河南工学院 | 2018-05-08 | — | — | CN | claimed |
| JP-57131382-A | — | — | None | — | — | JP | disclosed |
| CN-110872248-B | Multifunctional cationic fluorescent probe based on amido thiourea and preparation method thereof | 华南师范大学 | 2021-05-25 | — | — | CN | disclosed |
| CN-110872248-A | Multifunctional cationic fluorescent probe based on amido thiourea and preparation method thereof | 华南师范大学 | 2020-03-10 | — | — | CN | disclosed |
| CN-107245044-B | 2- (naphthylamino thioformyl) hydrazine benzyl formate compound, synthetic method and application | 华南师范大学 | 2019-11-15 | — | — | CN | disclosed |
| CN-108007909-A | Carbon quantum dot is in detection Fe after the modification of 4- naphthyl -3- thiosemicarbazides3+In application | 河南工学院 | 2018-05-08 | — | — | CN | disclosed |
| CN-107245044-A | 2‑（Naphthylamino thioformyl）Hydrazine benzyl formate compound, synthetic method and application | 华南师范大学 | 2017-10-13 | — | — | CN | disclosed |
| EP-2240175-B1 | COMPOUNDS WITH MDR1-INVERSE ACTIVITY | US GOV HEALTH & HUMAN SERV (US) | 2013-01-02 | — | — | EP | disclosed |
| EP-1569919-B1 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2012-04-18 | — | — | EP | disclosed |
| WO-2012033601-A1 | THIOSEMICARBAZONES WITH MDR1 - INVERSE ACTIVITY | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES (US) | 2012-03-15 | — | — | WO | disclosed |
| US-20040058990-A1 | Thrombopoietin mimetics | SMITHKLINE BEECHAM CORPORATION | 2004-03-25 | — | — | US | disclosed |
| EP-1349613-A2 | THROMBOPOIETIN MIMETICS | SmithKline Beecham Corporation (US) | 2003-10-08 | — | — | EP | disclosed |
| WO-2002049413-A2 | THROMBOPOIETIN MIMETICS | SMITHKLINE BEECHAM CORPORATION (US) | 2002-06-27 | — | — | WO | disclosed |
| US-5194139-A | Antideposit agents | NIPPON MINING COMPANY LIMITED (JP) | 1993-03-16 | — | — | US | disclosed |
| US-4871737-A | 3-Amino-5-methyl-1H-pyrazole-4-carboxylic acids and esters thereof as anticonvulsants muscle relaxants and anxiolytics | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-10-03 | — | — | US | disclosed |
| EP-0315433-A2 | 3-amino-5-methyl-1H-pyrazole-4-carboxylic acids and esters thereof as anticonvulsants, muscle relaxants and anxiolytics | A.H. ROBINS COMPANY, INCORPORATED (US) | 1989-05-10 | — | — | EP | disclosed |
| US-4826866-A | 3-amino-5-methyl-1H-pyrazole-4-carboxylic acids and esters thereof as anticonvulsants, muscle relaxants and anxiolytics | A. H. ROBINS COMPANY, INCORPORATED (US) | 1989-05-02 | — | — | US | disclosed |
| US-4452673-A | DITHIOCARBAMIC ACIDS AND/OR THIOSEMICARBAZIDES | SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) | 1984-06-05 | — | — | US | disclosed |
| JP-S57131382-A | SILVER PLATING SOLUTION | SUMITOMO ELECTRIC IND LTD | 1982-08-14 | — | — | JP | disclosed |
| US-3940408-A | CORROSION INHIBITORS IN LUBRICANTS | TEXACO INC. (US) | 1976-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058990-A1 | Thrombopoietin mimetics | MPL, THPO, TEK | GAA 3120/4885ALDH1A1 1889/4885KMT2A 2928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.