Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | ITGAV | P06756 | 2/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 4/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.42 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 3/20 | 0.41 |
| ▸ | PKLR | P30613 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4621222 | 1.00 | NPC1 (0.46) | NPC1ITGAVCTSDHPGDTP53 | |
| SCHEMBL4621354 | 1.00 | NPC1 (0.46) | NPC1ITGAVCTSDHPGDTP53 | |
| SCHEMBL4622868 | 0.82 | HPGD (0.49) | NPC1CTSDHPGDTP53GLA | |
| SCHEMBL4620643 | 0.82 | HPGD (0.49) | NPC1CTSDHPGDTP53GLA | |
| SCHEMBL4619909 | 0.82 | HPGD (0.49) | NPC1CTSDHPGDTP53GLA | |
| SCHEMBL2794042 | 0.81 | HPGD (0.61) | NPC1CTSDHPGDTP53GLA | |
| SCHEMBL12984069 | 0.81 | HPGD (0.61) | NPC1CTSDHPGDTP53GLA | |
| SCHEMBL4622116 | 0.78 | ITGAV (0.70) | ITGAVPKLR | |
| SCHEMBL4621068 | 0.78 | ITGAV (0.70) | ITGAVPKLR | |
| SCHEMBL4621521 | 0.78 | ITGAV (0.70) | ITGAVPKLR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1884230-A1 | PARAKERATOSIS INHIBITOR, PORE-SHRINKING AGENT OR AGENT FOR PREVENTING/AMELIORATING ROUGH SKIN AND EXTERNAL COMPOSITION FOR SKIN | Shiseido Company, Limited (JP) | 2008-02-06 | — | — | EP | disclosed |