Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.42 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4622868 | 1.00 | HPGD (0.49) | HPGDALDH1A1NPC1RAB9ACTSD | |
| SCHEMBL4620643 | 1.00 | HPGD (0.49) | HPGDALDH1A1NPC1RAB9ACTSD | |
| SCHEMBL4623965 | 0.82 | NPC1 (0.46) | HPGDALDH1A1NPC1RAB9ACTSD | |
| SCHEMBL4621222 | 0.82 | NPC1 (0.46) | HPGDALDH1A1NPC1RAB9ACTSD | |
| SCHEMBL4621354 | 0.82 | NPC1 (0.46) | HPGDALDH1A1NPC1RAB9ACTSD | |
| SCHEMBL4620829 | 0.77 | ADAMTS4 (0.53) | HPGDALDH1A1KMT2AADAMTS4HTT | |
| SCHEMBL4620791 | 0.77 | ADAMTS4 (0.53) | HPGDALDH1A1KMT2AADAMTS4HTT | |
| SCHEMBL4621468 | 0.77 | ADAMTS4 (0.53) | HPGDALDH1A1KMT2AADAMTS4HTT | |
| SCHEMBL4620131 | 0.77 | ITGAV (0.60) | HPGDALDH1A1KMT2AADAMTS4HSD17B10 | |
| SCHEMBL4622372 | 0.77 | ITGAV (0.60) | HPGDALDH1A1KMT2AADAMTS4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1884230-A1 | PARAKERATOSIS INHIBITOR, PORE-SHRINKING AGENT OR AGENT FOR PREVENTING/AMELIORATING ROUGH SKIN AND EXTERNAL COMPOSITION FOR SKIN | Shiseido Company, Limited (JP) | 2008-02-06 | — | — | EP | disclosed |