Di(Hydroxyethyl)Ether

Di(Hydroxyethyl)Ether

SCHEMBL4624074

C=C(CC(CC)CCCC)C(=O)OC.OCCOCCO

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.40
ALDH1A1 P00352 3/20 0.39
MMP9 P14780 1/20 0.39
MMP8 P22894 1/20 0.39
MMP14 P50281 1/20 0.39
CA2 P00918 4/20 0.37
CA1 P00915 1/20 0.37
CYP3A4 P08684 5/20 0.37
ATM Q13315 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
MEN1 O00255 1/20 0.37
THRB P10828 1/20 0.37
HTT P42858 1/20 0.37
KMT2A Q03164 1/20 0.37
MAPT P10636 1/20 0.37
RECQL P46063 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.33
ACHE P22303 1/20 0.33
HRH4 Q9H3N8 1/20 0.32
HRH3 Q9Y5N1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20578185 0.90 TSHR (0.45) TSHRALDH1A1MMP9MMP8MMP14
SCHEMBL1110719 0.88 TSHR (0.40) TSHRALDH1A1MMP9MMP8MMP14
Di(Hydroxyethyl)Ether SCHEMBL28694992 0.86 TSHR (0.42) TSHRALDH1A1MMP9MMP8MMP14
SCHEMBL11326788 0.84 TSHR (0.44) TSHRALDH1A1MMP9MMP8MMP14
Acrylic Acid SCHEMBL28097267 0.82 TSHR (0.49) TSHRALDH1A1MMP9MMP8MMP14
SCHEMBL10627515 0.80 THRB (0.43) TSHRALDH1A1MMP9MMP8MMP14
SCHEMBL1759450 0.79 TSHR (0.47) TSHRALDH1A1MMP9MMP8MMP14
SCHEMBL28120881 0.79 TSHR (0.44) TSHRALDH1A1CA2CA1CYP3A4
SCHEMBL3102870 0.79 TSHR (0.46) TSHRALDH1A1MMP9MMP8MMP14
SCHEMBL27858348 0.78 MEN1 (0.36) TSHRALDH1A1MMP9MMP8MMP14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1424210-B1 PHOTOSENSITIVE RESIN COMPOSITION AND LASER ENGRAVABLE PRINTING ELEMENT ASAHI KASEI CHEMICALS CORP (JP) 2008-05-14 EP disclosed
EP-1516745-B1 PHOTOSENSITIVE RESIN COMPOSITION FOR FORMING A LASER ENGRAVABLE PRINTING ELEMENT ASAHI KASEI CHEMICALS CORP (JP) 2007-02-14 EP disclosed
EP-1516745-A1 PHOTOSENSITIVE RESIN COMPOSITION FOR ORIGINAL PRINTING PLATE CAPABLE OF BEING CARVED BY LASER Asahi Kasei Chemicals Corporation (JP) 2005-03-23 EP disclosed
EP-1424210-A1 PHOTOSENSITIVE RESIN COMPOSITION FOR PRINTING PLATE PRECURSOR CAPABLE OF LASER ENGRAVING Asahi Kasei Chemicals Corporation (JP) 2004-06-02 EP disclosed