Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | ABL1 | P00519 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | IDE | P14735 | 1/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.65 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.56 |
| ▸ | HLCS | P50747 | 3/20 | 0.54 |
| ▸ | CA12 | O43570 | 5/20 | 0.53 |
| ▸ | CA1 | P00915 | 5/20 | 0.53 |
| ▸ | CA2 | P00918 | 5/20 | 0.53 |
| ▸ | CA9 | Q16790 | 5/20 | 0.53 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.51 |
| ▸ | PTPRF | P10586 | 2/20 | 0.51 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10140261 | 0.93 | TDP1 (0.62) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL2458624 | 0.93 | TDP1 (0.62) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL29400740 | 0.91 | TDP1 (0.65) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL31378143 | 0.91 | TDP1 (0.68) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL31378084 | 0.90 | TDP1 (0.63) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL31378057 | 0.89 | TDP1 (0.69) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL31378085 | 0.89 | TDP1 (0.63) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL31248180 | 0.89 | TDP1 (0.69) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL31332171 | 0.88 | CAPN1 (0.62) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL5832621 | 0.87 | TDP1 (0.61) | TDP1MEN1ABL1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1356036-B1 | PROCESS AND COMPOSITIONS FOR PEPTIDE, PROTEIN AND PEPTIDOMIMETIC SYNTHESIS | FORSTER ANTHONY C (US) | 2008-05-07 | — | — | EP | claimed |
| US-6977150-B2 | Process and compositions for peptide, protein and peptidomimetic synthesis | Forster, Anthony C. (US) | 2005-12-20 | — | — | US | claimed |
| US-20040091955-A1 | Process and compositions for peptide, protein and peptidomimetic synthesis | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-05-13 | — | — | US | claimed |
| EP-1356036-A2 | PROCESS AND COMPOSITIONS FOR PEPTIDE, PROTEIN AND PEPTIDOMIMETIC SYNTHESIS | Forster, Anthony C. (US) | 2003-10-29 | — | — | EP | claimed |
| WO-2002059293-A2 | PROCESS AND COMPOSITIONS FOR PEPTIDE, PROTEIN AND PEPTIDOMIMETIC SYNTHESIS | FORSTER ANTHONY C (US) | 2002-08-01 | — | — | WO | claimed |
| CN-120136957-A | Mild method for synthesizing polypeptide containing more than two pairs of disulfide bonds | 南京金斯瑞生物科技有限公司 | 2025-06-13 | — | — | CN | disclosed |
| CN-119470877-A | Biotinylation modified amino acid probe, preparation method and application thereof, and method and application for identifying amino acid binding protein | 同济大学 | 2025-02-18 | — | — | CN | disclosed |
| EP-2870180-B1 | ANTI-BIOTIN ANTIBODIES AND METHODS OF USE | HOFFMANN LA ROCHE (CH) | 2024-08-28 | — | — | EP | disclosed |
| US-12023378-B2 | Covalently linked antigen-antibody conjugates | HOFFMANN-LA ROCHE INC. (US) | 2024-07-02 | — | — | US | disclosed |
| CN-118184737-A | Polypeptide or mutant thereof specifically binding erythrocyte membrane | 北京睿脉医药科技有限公司 | 2024-06-14 | — | — | CN | disclosed |
| US-11273223-B2 | Bispecific anti-hapten/anti-blood brain barrier receptor antibodies, complexes thereof and their use as blood brain barrier shuttles | HOFFMANN-LA ROCHE INC. (US) | 2022-03-15 | — | — | US | disclosed |
| EP-3960768-A1 | BISPECIFIC ANTI-HAPTEN/ANTI-BLOOD BRAIN BARRIER RECEPTOR ANTIBODIES, COMPLEXES THEREOF AND THEIR USE AS BLOOD BRAIN BARRIER SHUTTLES | F. Hoffmann-La Roche AG (CH) | 2022-03-02 | — | — | EP | disclosed |
| EP-1356036-B1 | PROCESS AND COMPOSITIONS FOR PEPTIDE, PROTEIN AND PEPTIDOMIMETIC SYNTHESIS | FORSTER ANTHONY C (US) | 2008-05-07 | — | — | EP | disclosed |
| EP-1859042-A2 | NOVEL HUMAN, FELINE, CHICKEN AND OTHER ANIMAL INTERFERONS AND USES THEREOF | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 2007-11-28 | — | — | EP | disclosed |
| WO-2006099451-A2 | NOVEL HUMAN, FELINE, CHICKEN AND OTHER ANIMAL INTERFERONS AND USES THEREOF | UNIVERSITY OF MEDICINE & DENTISTRY OF NEW JERSEY (US) | 2006-09-21 | — | — | WO | disclosed |
| US-6977150-B2 | Process and compositions for peptide, protein and peptidomimetic synthesis | Forster, Anthony C. (US) | 2005-12-20 | — | — | US | disclosed |
| US-20040091955-A1 | Process and compositions for peptide, protein and peptidomimetic synthesis | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-05-13 | — | — | US | disclosed |
| EP-1356036-A2 | PROCESS AND COMPOSITIONS FOR PEPTIDE, PROTEIN AND PEPTIDOMIMETIC SYNTHESIS | Forster, Anthony C. (US) | 2003-10-29 | — | — | EP | disclosed |
| WO-2002059293-A2 | PROCESS AND COMPOSITIONS FOR PEPTIDE, PROTEIN AND PEPTIDOMIMETIC SYNTHESIS | FORSTER ANTHONY C (US) | 2002-08-01 | — | — | WO | disclosed |