Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | ABL1 | P00519 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | IDE | P14735 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 6/20 | 0.55 |
| ▸ | CA1 | P00915 | 6/20 | 0.55 |
| ▸ | CA2 | P00918 | 6/20 | 0.55 |
| ▸ | CA9 | Q16790 | 6/20 | 0.55 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.51 |
| ▸ | HLCS | P50747 | 2/20 | 0.50 |
| ▸ | PTPRF | P10586 | 2/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29400740 | 0.89 | TDP1 (0.65) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL4624128 | 0.87 | TDP1 (0.65) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL31378143 | 0.87 | TDP1 (0.68) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL31378084 | 0.86 | TDP1 (0.63) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL31248180 | 0.85 | TDP1 (0.69) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL31378057 | 0.85 | TDP1 (0.69) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL31378085 | 0.85 | TDP1 (0.63) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL9807479 | 0.85 | TDP1 (0.77) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL31332171 | 0.84 | CAPN1 (0.62) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL10140261 | 0.84 | TDP1 (0.62) | TDP1MEN1ABL1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040180381-A1 | Method for determining amino acid sequence of a peptide | SHIMADZU CORPORATION (JP) | 2004-09-16 | — | — | US | claimed |
| US-7041472-B2 | Method for selectively collecting N-terminal peptide fragment of protein | SHIMADZU CORPORATION (JP) | 2006-05-09 | — | — | US | disclosed |
| US-20040180381-A1 | Method for determining amino acid sequence of a peptide | SHIMADZU CORPORATION (JP) | 2004-09-16 | — | — | US | disclosed |
| US-20040152155-A1 | Method for selectively collecting N-terminal peptide fragment of protein | SHIMADZU CORPORATION (JP) | 2004-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040180381-A1 | Method for determining amino acid sequence of a peptide | VIP, ANPEP, DNPEP | TDP1 2820/4885MEN1 940/4885ABL1 2829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.